Evidence map›Paper›PMID 35409398›Full record

ArticleInternational journal of molecular sciences2022

Identification of Codon 146

Aude Beyens, Laure Dequeker, Hilde Brems, Sandra Janssens, Hannes Syryn, Anne D'Hooghe, Pascale De Paepe, Lieve Vanwalleghem, Annelies Stockman, Elena Vankwikelberge and 4 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Cancer in Multilineage Mosaic RASopathies due to Pathogenic Variants in HRAS or KRAS: A Systematic Review and Meta-analysis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Pooled it
  2. Article
  3. Article
  4. Editorial: Special Issue, "Molecular Advances in Skin Diseases".International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Aude BeyensCenter for Medical Genetics Ghent, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0003-0231-6861
Laure DequekerDepartment of Ophthalmology, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Hilde BremsDepartment of Human Genetics, University Hospital Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-0325-4060
Sandra JanssensCenter for Medical Genetics Ghent, Ghent University Hospital, 9000 Ghent, Belgium.
Hannes SyrynCenter for Medical Genetics Ghent, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-0914-2676
Anne D'HoogheDepartment of Pediatrics, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Pascale De PaepeDepartment of Pathology, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Lieve VanwalleghemDepartment of Pathology, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Annelies StockmanDepartment of Dermatology, General Hospital Delta Roeselare-Menen-Torhout, 8820 Torhout, Belgium.
Elena VankwikelbergeDepartment of Dermatology, Ghent University Hospital, 9000 Ghent, Belgium.
Sofie De SchepperDepartment of Dermatology, Ghent University Hospital, 9000 Ghent, Belgium.
Marleen GoeteynDepartment of Dermatology, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Patricia DelbekeDepartment of Ophthalmology, General Hospital Sint-Jan Brugge-Oostende, 8000 Bruges, Belgium.
Bert CallewaertCenter for Medical Genetics Ghent, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-9743-4205
Ghent University Hospital · BEAZ Sint-Jan · BEKU Leuven · BE

Funding

European Academy of Dermatology and Venereology PPRC-2018-50Research Foundation - Flanders G035620NSpecial Research Fund, Flanders of Ghent University 01N04516C
6 · The paper itself

Abstract

Mosaic RASopathies are a molecularly heterogeneous group of (neuro)cutaneous syndromes with high phenotypical variability. Postzygotic variants in

Indexed as

HamartomaNevusCodonDermoid CystEctodermal DysplasiaEye DiseasesHumansLipomatosisNeurocutaneous SyndromesProto-Oncogene Proteins p21(ras)CodonKRAS protein, humanProto-Oncogene Proteins p21(ras)didymosisencephalocraniocutaneous syndromeepibulbar dermoidepidermal nevusKRASnevus psiloliparusnon-allelic twin spottingoculoectodermal syndromeRASopathy

Identifiers

PMID35409398
PMCPMC8999796
OpenAlexW4223604221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.