Evidence map›Paper›PMID 35409354›Full record

ReviewInternational journal of molecular sciences2022

Circulating microRNAs in Medicine.

Tetiana Pozniak, Dzmitry Shcharbin, Maria Bryszewska

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07231731 (Association of MicroRNA-151-5p Expression With Systemic Inflammatory Response and Cognitive Status in Patients After Coronary Artery Bypass Surgery), which is not on this map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07231731 completednot on this map

Association of MicroRNA-151-5p Expression With Systemic Inflammatory Response and Cognitive Status in Patients After Coronary Artery Bypass Surgery (MiRNACOG)

Typeobservational_patient_registrySponsorOsijek University HospitalRan2022 to 2023Enrolled48ConditionsBiomarkers, Coronary Artery Bypass Surgery, Interleukin-6, MicroRNAs
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
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  14. Non-coding RNA profiling in BRAFScientific data · 2025
    Article
  15. Article
  16. Review
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  19. Review
  20. Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Tetiana PozniakInstitute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus, 220072 Minsk, Belarus.
Dzmitry ShcharbinInstitute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus, 220072 Minsk, Belarus.ORCID 0000-0002-1414-4465
Maria BryszewskaDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 90-236 Lodz, Poland.ORCID 0000-0003-4676-3743
National Academy of Sciences of Belarus · BYNational Academy of Sciences of Ukraine · UAUniversity of Łódź · PL

Funding

Belarusian Republican Foundation for Fundamental Research and State Committee of Science and Technology of Belarus B20SLKG-002, B21KORG-001, B21TUB-001, B21ARMG-002, B21RM-045, and B21M-001Polish National Agency for Academic Exchange, grant EUROPARTNER, No. PPI/APM/2018/1/00007/U/001
6 · The paper itself

Abstract

Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological fluids, are promising sensitive biomarkers for various diseases (oncological and cardiovascular diseases, neurodegenerative pathologies, etc.), and their signatures accurately reflect the state of the body. Studies of the expression of microRNA markers show that they can enable a wide range of diseases to be diagnosed before clinical symptoms are manifested, and they can help to assess a patient's response to therapy in order to correct and personalize treatments. This review discusses the latest trends in the uses of miRNAs for diagnosing and treating various diseases, viral and non-viral. It is concluded that exogenous microRNAs can be used as high-precision therapeutic agents for these purposes.

Indexed as

Cardiovascular DiseasesCirculating MicroRNAMedicineMicroRNAsBiomarkersHumansBiomarkersCirculating MicroRNAMicroRNAscardiovascular diseasescirculating microRNAs (c-microRNAs, c-miRNAs)neurodegenerative diseasesoncologysmall interfering RNAs (miRNAs)

Identifiers

PMID35409354
PMCPMC8999557
OpenAlexW4223460450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.