Evidence map›Paper›PMID 35409344›Full record

ArticleInternational journal of molecular sciences2022

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation.

Aurélie Philippe, Gunnar Kleinau, Jason Jannis Gruner, Sumin Wu, Daniel Postpieszala, David Speck, Harald Heidecke, Simon J Dowell, Gabriela Riemekasten, Peter W Hildebrand and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Aurélie PhilippeBerlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, D-10178 Berlin, Germany.
Gunnar KleinauCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, D-10117 Berlin, Germany.
Jason Jannis GrunerCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Nephrology and Medical Intensive Care, Campus Virchow Klinikum, D-13353 Berlin, Germany.
Sumin WuCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Nephrology and Medical Intensive Care, Campus Virchow Klinikum, D-13353 Berlin, Germany.
Daniel PostpieszalaCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Nephrology and Medical Intensive Care, Campus Virchow Klinikum, D-13353 Berlin, Germany.
David SpeckCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, D-10117 Berlin, Germany.
Harald HeideckeCellTrend GmbH, D-14943 Luckenwalde, Germany.
Simon J DowellGlaxoSmithKline, Stevenage SG1 2NY, UK.ORCID 0000-0001-6499-7573
Gabriela RiemekastenPriority Area Asthma & Allergy, Research Center Borstel, Airway Research Center North (ARCN), Members of the German Center for Lung Research (DZL), D-23845 Borstel, Germany.
Peter W HildebrandCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, D-10117 Berlin, Germany.ORCID 0000-0003-0063-1104
Julian Kamhieh-MilzCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Transfusion Medicine, D-10117 Berlin, Germany.
Rusan CatarCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Nephrology and Medical Intensive Care, Campus Virchow Klinikum, D-13353 Berlin, Germany.ORCID 0000-0002-7000-7860
Michal SzczepekCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, D-10117 Berlin, Germany.
Duska DragunBerlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, D-10178 Berlin, Germany.
Patrick ScheererCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal Transduction, D-10117 Berlin, Germany.ORCID 0000-0001-5028-2075
Humboldt-Universität zu Berlin · DEGerman Center for Lung Research · DEGlaxoSmithKline (United Kingdom) · GBInstitute of Pathology Celle · DE

Funding

Deutsche Forschungsgemeinschaft 25065445Deutsche Forschungsgemeinschaft 394046635Deutsche Forschungsgemeinschaft 421152132European Union 956314
6 · The paper itself

Abstract

The angiotensin II (Ang II) type 1 receptor (AT

Indexed as

AntibodiesReceptor, Angiotensin, Type 1AlanineAngiotensin IICell ProliferationHEK293 CellsHumansAlanineAngiotensin IIAntibodiesReceptor, Angiotensin, Type 1angiotensinangiotensin II type 1 receptorAT1Rauto-antibodiesendothelinG protein-coupled receptorssystemic sclerosis

Identifiers

PMID35409344
PMCPMC8999261
OpenAlexW4223620042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.