ArticleInternational journal of molecular sciences2022
Antisense Oligonucleotide Induction of the hnRNPA1b Isoform Affects Pre-mRNA Splicing of
Jarichad Toosaranont, Sukanya Ruschadaariyachat, Warasinee Mujchariyakul, Jantarika Kumar Arora, Varodom Charoensawan, Bhoom Suktitipat, Thomas N Palmer, Sue Fletcher, Steve D Wilton, Chalermchai Mitrpant
Open access · goldAbstract read
In one paragraphArticle in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors at 4 institutions in 3 countries.
Jarichad ToosaranontDepartment of Biochemistry, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Sukanya RuschadaariyachatDepartment of Biochemistry, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Warasinee MujchariyakulDepartment of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10700, Thailand.
Jantarika Kumar AroraDepartment of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0002-8025-0557 Varodom CharoensawanDepartment of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10700, Thailand.
Bhoom SuktitipatDepartment of Biochemistry, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0001-8034-7757 Thomas N PalmerPerron Institute for Neurological and Translational Science, The University of Western Australia, Perth, WA 6009, Australia.
Sue FletcherPerron Institute for Neurological and Translational Science, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0002-8632-641X Steve D WiltonPerron Institute for Neurological and Translational Science, The University of Western Australia, Perth, WA 6009, Australia.
Chalermchai MitrpantDepartment of Biochemistry, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID 0000-0001-9311-7977 Siriraj Hospital · THMahidol University · THMurdoch University · AUThe University of Western Australia · AU
Funding
Research Development fund, Faculty of Medicine, Siriraj Hospital R0158333001Thailand Research Fund TRG5880047
6 · The paper itselfAbstract
Spinal muscular atrophy (SMA) is a severe, debilitating neuromuscular condition characterised by loss of motor neurons and progressive muscle wasting. SMA is caused by a loss of expression of
Indexed as
Muscular Atrophy, SpinalSpinal Muscular Atrophies of ChildhoodFibroblastsHumansOligonucleotidesOligonucleotides, AntisenseProtein IsoformsRNA PrecursorsRNA SplicingSurvival of Motor Neuron 1 ProteinSurvival of Motor Neuron 2 ProteinOligonucleotidesOligonucleotides, AntisenseProtein IsoformsRNA PrecursorsSMN2 protein, humanSurvival of Motor Neuron 1 ProteinSurvival of Motor Neuron 2 Proteinantisense oligonucleotidehnRNPA1phosphorodiamidate morpholino oligomerspinal muscular atrophytranscriptome
Identifiers
PMID35409296
PMCPMC8999010
OpenAlexW4223538314
What OpenQuestion holds
Textmetadata
LicenceCC BY
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