Evidence map›Paper›PMID 35409216›Full record

ArticleInternational journal of molecular sciences2022

Acute and Delayed Effects of Mechanical Injury on Calcium Homeostasis and Mitochondrial Potential of Primary Neuroglial Cell Culture: Potential Causal Contributions to Post-Traumatic Syndrome.

Zanda Bakaeva, Mikhail Goncharov, Irina Krasilnikova, Arina Zgodova, Daniil Frolov, Ekaterina Grebenik, Peter Timashev, Vsevolod Pinelis, Alexander Surin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Zanda BakaevaLaboratory of Neurobiology and Fundamentals of Brain Development, National Medical Research Center of Children's Health, 119991 Moscow, Russia.ORCID 0000-0002-2797-3270
Mikhail GoncharovCenter of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Irina KrasilnikovaLaboratory of Neurobiology and Fundamentals of Brain Development, National Medical Research Center of Children's Health, 119991 Moscow, Russia.ORCID 0000-0001-9453-3040
Arina ZgodovaLaboratory of Neurobiology and Fundamentals of Brain Development, National Medical Research Center of Children's Health, 119991 Moscow, Russia.
Daniil FrolovInstitute of Information Technologies, MIREA-Russian Technological University, 119454 Moscow, Russia.
Ekaterina GrebenikInstitute for Regenerative Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146 Moscow, Russia.
Peter TimashevInstitute for Regenerative Medicine, Sechenov First Moscow State Medical University (Sechenov University), 119146 Moscow, Russia.ORCID 0000-0001-7773-2435
Vsevolod PinelisLaboratory of Neurobiology and Fundamentals of Brain Development, National Medical Research Center of Children's Health, 119991 Moscow, Russia.
Alexander SurinLaboratory of Neurobiology and Fundamentals of Brain Development, National Medical Research Center of Children's Health, 119991 Moscow, Russia.
Sechenov University · RUScientific Center of Children's Health · RUKalmyk State University · RUMIREA - Russian Technological University · RUResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUSkolkovo Institute of Science and Technology · RU

Funding

Russian Ministry of Health АААА-А19-119012590191-3Russian Science Foundation 17-00-00106
6 · The paper itself

Abstract

In vitro models of traumatic brain injury (TBI) help to elucidate the pathological mechanisms responsible for cell dysfunction and death. To simulate in vitro the mechanical brain trauma, primary neuroglial cultures were scratched during different periods of network formation. Fluorescence microscopy was used to measure changes in intracellular free Ca

Indexed as

Brain Injuries, TraumaticCalciumHomeostasisHumansMitochondriaNeurogliaCalcium[Ca2+]iGFAPmechanical traumaneuroglial cultureneuroreparationNMDARpost-traumatic syndromeβ-III tubulinΔΨm

Identifiers

PMID35409216
PMCPMC8998891
OpenAlexW4220954862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.