Evidence map›Paper›PMID 35409174›Full record

ArticleInternational journal of molecular sciences2022

Enhanced Survival of High-Risk Medulloblastoma-Bearing Mice after Multimodal Treatment with Radiotherapy, Decitabine, and Abacavir.

Marieke Gringmuth, Jenny Walther, Sebastian Greiser, Magali Toussaint, Benjamin Schwalm, Marcel Kool, Rolf-Dieter Kortmann, Annegret Glasow, Ina Patties

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Marieke GringmuthDepartment of Radiation Oncology, University of Leipzig, Stephanstraße 9a, 04103 Leipzig, Germany.
Jenny WaltherFraunhofer Center for Microelectronic and Optical Systems for Biomedicine, Herman-Hollerith-Straße 3, 99099 Erfurt, Germany.
Sebastian GreiserFraunhofer Center for Microelectronic and Optical Systems for Biomedicine, Herman-Hollerith-Straße 3, 99099 Erfurt, Germany.
Magali ToussaintDepartment of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Research Site Leipzig, Permoserstraße 15, 04318 Leipzig, Germany.ORCID 0000-0002-1136-3857
Benjamin SchwalmHopp Children's Cancer Center (KiTZ), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.
Marcel KoolHopp Children's Cancer Center (KiTZ), Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.
Rolf-Dieter KortmannDepartment of Radiation Oncology, University of Leipzig, Stephanstraße 9a, 04103 Leipzig, Germany.
Annegret GlasowDepartment of Radiation Oncology, University of Leipzig, Stephanstraße 9a, 04103 Leipzig, Germany.
Ina PattiesDepartment of Radiation Oncology, University of Leipzig, Stephanstraße 9a, 04103 Leipzig, Germany.ORCID 0000-0001-6101-3145
Leipzig University · DEFraunhofer Institute for Cell Therapy and Immunology · DEGerman Cancer Research Center · DEHelmholtz-Zentrum Dresden-Rossendorf · DE

Funding

Else Kröner-Fresenius-Stiftung 2016_A184Janssen-Cilag GmbH DEC-I-17-DEU-001-V01Leipzig University xxx
6 · The paper itself

Abstract

Children with high-risk SHH/

Indexed as

Cerebellar NeoplasmsMedulloblastomaAbacavirAnimalsCell Line, TumorCombined Modality TherapyDecitabineDideoxynucleosidesHedgehog ProteinsHumansKi-67 AntigenMiceAbacavirDecitabineDideoxynucleosidesHedgehog ProteinsKi-67 Antigenabacavirbioluminescence imagingdecitabinegene expression microarrayin vivo studymagnetic resonance imagingmedulloblastomaradiationT2 mapping

Identifiers

PMID35409174
PMCPMC8998934
OpenAlexW4220854107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.