Evidence map›Paper›PMID 35409075›Full record

ArticleInternational journal of molecular sciences2022

PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients.

Dóra Szabó, Zsolt Sárszegi, Beáta Polgár, Éva Sághy, Dóra Reglődi, Tünde Tóth, Zsófia Onódi, Przemyslaw Leszek, Zoltán V Varga, Zsuzsanna Helyes and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Calcitonin/PACTrends in pharmacological sciences · 2023
    Review
  3. Article
  4. Diagnostic and Prognostic Value of PACAP in Multiple Myeloma.International journal of molecular sciences · 2023
    Article
  5. Article
  6. Role of endocrine PACAP in age-related diseases.Frontiers in endocrinology · 2023
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Dóra SzabóHeart Institute, Clinical Centre, Medical School, University of Pecs, 7624 Pecs, Hungary.
Zsolt SárszegiHeart Institute, Clinical Centre, Medical School, University of Pecs, 7624 Pecs, Hungary.
Beáta PolgárDepartment of Medical Microbiology and Immunology, Clinical Centre, Medical School, University of Pecs, 7624 Pecs, Hungary.
Éva SághyCardiometabolic Research Group, MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.
Dóra ReglődiDepartment of Anatomy, MTA-PTE PACAP Research Team, Centre for Neuroscience, Medical School, University of Pecs, 7624 Pecs, Hungary.
Tünde TóthDepartment of Anatomy, MTA-PTE PACAP Research Team, Centre for Neuroscience, Medical School, University of Pecs, 7624 Pecs, Hungary.
Zsófia OnódiCardiometabolic Research Group, MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-3746-8016
Przemyslaw LeszekDepartment of Heart Failure and Transplantology, Cardinal Stefan Wyszyński National Institute of Cardiology, 04-628 Warszawa, Poland.ORCID 0000-0003-4529-2687
Zoltán V VargaCardiometabolic Research Group, MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.ORCID 0000-0002-2758-0784
Zsuzsanna HelyesSzentagothai Research Centre, University of Pecs, 7624 Pecs, Hungary.
Ágnes KeménySzentagothai Research Centre, University of Pecs, 7624 Pecs, Hungary.
Péter FerdinandyCardiometabolic Research Group, MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089 Budapest, Hungary.
Andrea TamásDepartment of Anatomy, MTA-PTE PACAP Research Team, Centre for Neuroscience, Medical School, University of Pecs, 7624 Pecs, Hungary.
University of Pecs · HUSemmelweis University · HUInstitute of Cardiology · PL

Funding

European Union's Horizon 2020 research and innovation program under grant agreement No 739593GINOP 2.3.2-15-2016-00050 "PEPSYS"Hungarian Academy of Sciences MTA-TKI 14016Hungarian Scientific Research Fund K119759, K129190, K135457János Bolyai Research Scholarships of the Hungarian Academy of Sciences'National Heart Program NVKP_16-1-2016-0017National Research, Development and Innovation Office (NKFIH) of Hungary FK134751Thematic Excellence Program 2021 Health Sub-programme of the Ministry for Innovation and Technology in Hungary, within the framework of the EGA-16 project of the Pécs of University, University of Pecs Medical School KA Research Grant KA-2019-30ÚNKP-19-4 New National Excellence Program of the Ministry for Innovation and Technology ÚNKP-19-4
6 · The paper itself

Abstract

Pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) is a multifunctional neuropeptide, which may play a role in cardioprotection. However, little is known about the presence of PACAP-38 in heart failure (HF) patients. The aim of our study was to measure the alterations of PACAP-38 like immunoreactivity (LI) in acute (

Indexed as

Heart FailurePituitary Adenylate Cyclase-Activating PolypeptideHumansMyocardiumReceptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type IPituitary Adenylate Cyclase-Activating PolypeptideReceptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type Icytokinesheart failureischemic/non-ischemic cardiomyopathyNT-proBNPpituitary adenylate cyclase activating polypeptide

Identifiers

PMID35409075
PMCPMC8998504
OpenAlexW4220982924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.