Evidence map›Paper›PMID 35409046›Full record

ArticleInternational journal of molecular sciences2022

Combination Strategy of Genetic Dereplication and Manipulation of Epigenetic Regulators Reveals a Novel Compound from Plant Endophytic Fungus.

Lu Yang, Guangwei Wu, Fanyue Meng, Huomiao Ran, Wenbing Yin, Wei Li, Xiaoqing Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Genetic Dereplication of MultipleJournal of natural products · 2026
    Article
  2. Journal of fungi (Basel, Switzerland) · 2026
    Article
  3. Biosynthesis Regulation of Secondary Metabolite Production inJournal of fungi (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lu YangCollege of Life Science, Capital Normal University, Beijing 100048, China.
Guangwei WuJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Jiangsu Key Lab of Biomass-Based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Fanyue MengCollege of Life Science, Capital Normal University, Beijing 100048, China.
Huomiao RanState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
Wenbing YinState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-9184-3198
Wei LiState Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0001-6639-0441
Xiaoqing LiuCollege of Life Science, Capital Normal University, Beijing 100048, China.
Capital Normal University · CNChinese Academy of Sciences · CNNanjing Forestry University · CN

Funding

Biological Resources Program, Chinese Academy of Sciences KFJ-BRP-009National Key Research and Development Program of China 2021YFC2300400National Natural Science Foundation of China 31861133004Starting Research Fund from the Nanjing Forestry University No.163030196
6 · The paper itself

Abstract

The strategies of genetic dereplication and manipulation of epigenetic regulators to activate the cryptic gene clusters are effective to discover natural products with novel structure in filamentous fungi. In this study, a combination of genetic dereplication (deletion of pesthetic acid biosynthetic gene,

Indexed as

Biological ProductsFungiEpigenesis, GeneticEpigenomicsPlantsBiological Productsepigenetic regulationfilamentous fungigenetic dereplicationoxidative stresssecondary metabolites

Identifiers

PMID35409046
PMCPMC8998291
OpenAlexW4220739503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.