Evidence map›Paper›PMID 35409015›Full record

ArticleInternational journal of molecular sciences2022

Gliadin Peptide P31-43 Induces mTOR/NFkβ Activation and Reduces Autophagy: The Role of

Mariangela Conte, Federica Nigro, Monia Porpora, Claudia Bellomo, Francesca Furone, Andrea Luigi Budelli, Roberto Nigro, Maria Vittoria Barone, Merlin Nanayakkara

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. A Postbiotic Derived fromFoods (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Animals : an open access journal from MDPI · 2023
    Article
  14. Review
  15. Peculiar CaInternational journal of molecular sciences · 2023
    Article
  16. The protective role ofFrontiers in medicine · 2023
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mariangela ConteELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Federica NigroI.T.P. Innovation and Technology Provider s.r.l., Via Bisignano a Chiaia 68, 80121 Naples, Italy.
Monia PorporaELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Claudia BellomoELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0001-8983-6776
Francesca FuroneELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Andrea Luigi BudelliDICMAPI, University of Naples Federico II, 80125 Naples, Italy.ORCID 0000-0003-1866-1301
Roberto NigroDICMAPI, University of Naples Federico II, 80125 Naples, Italy.ORCID 0000-0002-9459-2128
Maria Vittoria BaroneELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0001-6190-4917
Merlin NanayakkaraELFID (European Laboratory for the Investigation of Food Induced Diseases), Department of Translational Medical Science, Section of Paediatrics, University Federico II, Via S. Pansini 5, 80131 Naples, Italy.
University of Naples Federico II · IT

Funding

Italian Association for Celiac Disease (AIC) Grant 005_FC_2016
6 · The paper itself

Abstract

Celiac disease (CD) is an autoimmune disease characterized by an altered immune response stimulated by gliadin peptides that are not digested and cause damage to the intestinal mucosa. The aim of this study was to investigate whether the postbiotic

Indexed as

Celiac DiseaseLacticaseibacillus paracaseiAutophagyCaco-2 CellsGliadinHumansInflammationIntestinal MucosaPeptide FragmentsPeptidesTOR Serine-Threonine KinasesGliadinMTOR protein, humanPeptide FragmentsPeptidesTOR Serine-Threonine Kinasesceliac disease (CD)gliadin peptide P31-43Lactobacillus paracasei CBA L74 postbiotcmTOR/NFkβ activation

Identifiers

PMID35409015
PMCPMC8999065
OpenAlexW4220821355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.