Evidence map›Paper›PMID 35408961›Full record

ArticleInternational journal of molecular sciences2022

Ascorbic Acid as an Adjuvant to Unbleached Cotton Promotes Antimicrobial Activity in Spunlace Nonwovens.

Judson Vincent Edwards, Nicolette T Prevost, Dorne Yager, Robert Mackin, Michael Santiago, SeChin Chang, Brian Condon, Joseph Dacorta

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Materials for Infectious Diseases.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Judson Vincent EdwardsSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
Nicolette T PrevostSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
Dorne YagerDepartment of Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.
Robert MackinSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.ORCID 0000-0002-1303-7393
Michael SantiagoSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
SeChin ChangSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
Brian CondonSouthern Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
Joseph DacortaH&H Medical, Williamsburg, VA 28135, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of affordable, effective, and environmentally friendly barrier fabrics is a current goal in antimicrobial textile development. The discovery of new routes to achieve non-toxic naturally occurring molecules with antimicrobial activity is of interest in the development of materials that promote wound healing, improve hygiene, and offer protection against nosocomial infection. Highly cleaned and sterile unbleached cotton has constituents that produce hydrogen peroxide at levels commensurate with those that favor cell signaling in wound healing. Here, we show the antimicrobial and antiviral properties of spunlaced griege cotton-containing nonwovens treated with ascorbic acid formulations. The mechanism of action occurs through the promotion of enhanced hydrogen peroxide activity. The levels of hydrogen peroxide activity afford antimicrobial activity against Gram-negative and Gram-positive bacteria and antiviral activity against MS2 bacteriophages. Spun-bond nonwoven unbleached cotton was treated with ascorbic acid using traditional pad-dry-cure methods. An assessment of antibacterial and antiviral activity against

Indexed as

Anti-Infective AgentsCotton FiberAdjuvants, PharmaceuticAnti-Bacterial AgentsAntiviral AgentsAscorbic AcidGossypiumHydrogen PeroxideTextilesAdjuvants, PharmaceuticAnti-Bacterial AgentsAnti-Infective AgentsAntiviral AgentsAscorbic AcidHydrogen Peroxideantimicrobial activityascorbic acidcotton

Identifiers

PMID35408961
PMCPMC8998428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.