Evidence map›Paper›PMID 35408957›Full record

ReviewInternational journal of molecular sciences2022

Mechanisms of Action of Non-Canonical ECF Sigma Factors.

Francisco Javier Marcos-Torres, Aurelio Moraleda-Muñoz, Francisco Javier Contreras-Moreno, José Muñoz-Dorado, Juana Pérez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Current models in bacterial hemicellulase-encoding gene regulation.Applied microbiology and biotechnology · 2024
    Review
  2. Article
  3. Article
  4. Implication of the σMicrobiology spectrum · 2023
    Article
  5. Review
  6. Bacterial Regulatory Proteins.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francisco Javier Marcos-TorresEstación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, 18011 Granada, Spain.ORCID 0000-0001-9453-7615
Aurelio Moraleda-MuñozDepartamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Avda, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0002-3330-5535
Francisco Javier Contreras-MorenoDepartamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Avda, Fuentenueva s/n, 18071 Granada, Spain.
José Muñoz-DoradoDepartamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Avda, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0001-7765-5687
Juana PérezDepartamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Avda, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0001-8073-9398

Funding

Spanish Government and FEDER funds PID2020-112634GB-I00 and A-BIO-126-UGR20
6 · The paper itself

Abstract

Extracytoplasmic function (ECF) sigma factors are subunits of the RNA polymerase specialized in activating the transcription of a subset of genes responding to a specific environmental condition. The signal-transduction pathways where they participate can be activated by diverse mechanisms. The most common mechanism involves the action of a membrane-bound anti-sigma factor, which sequesters the ECF sigma factor, and releases it after the stimulus is sensed. However, despite most of these systems following this canonical regulation, there are many ECF sigma factors exhibiting a non-canonical regulatory mechanism. In this review, we aim to provide an updated and comprehensive view of the different activation mechanisms known for non-canonical ECF sigma factors, detailing their inclusion to the different phylogenetic groups and describing the mechanisms of regulation of some of their representative members such as EcfG from

Indexed as

Gene Expression Regulation, BacterialSigma FactorBacterial ProteinsDNA-Directed RNA PolymerasesPhylogenyBacterial ProteinsDNA-Directed RNA PolymerasesSigma FactorECF sigma factorstress responsetranscriptional regulation

Identifiers

PMID35408957
PMCPMC8999054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.