Evidence map›Paper›PMID 35408890›Full record

ReviewInternational journal of molecular sciences2022

The Role of Endoplasmic Reticulum Stress and NLRP3 Inflammasome in Liver Disorders.

Xueqin Lu, Haitao Huang, Xiaodi Fu, Chaoran Chen, Huiyang Liu, Honggang Wang, Dongdong Wu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xueqin LuInstitute of Nursing and Health, School of Nursing and Health, Henan University, Jinming Avenue, Kaifeng 475004, China.
Haitao HuangInstitute of Nursing and Health, School of Nursing and Health, Henan University, Jinming Avenue, Kaifeng 475004, China.
Xiaodi FuSchool of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Chaoran ChenInstitute of Nursing and Health, School of Nursing and Health, Henan University, Jinming Avenue, Kaifeng 475004, China.
Huiyang LiuSchool of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Honggang WangSchool of Basic Medical Sciences, Henan University, Kaifeng 475004, China.ORCID 0000-0002-5617-3563
Dongdong WuSchool of Stomatology, Henan University, Kaifeng 475004, China.ORCID 0000-0001-6739-8437
Henan University · CN

Funding

CSRD VA 1the Graduate Education Reform and Quality Improvement Project of Henan Province YJS2021AL074the grants from key scientific and technological projects in Henan Province, China 202102310153the Henan Provincial Social Science Planning Decision Consulting Project 2018JC38the innovation and Entrepreneurship Training Program for Henan University Students in 2021 20211021002 and 20217003002
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) is a key organelle responsible for the synthesis, modification, folding and assembly of proteins; calcium storage; and lipid synthesis. When ER homeostatic balance is disrupted by a variety of physiological and pathological factors-such as glucose deficiency, environmental toxins, Ca

Indexed as

InflammasomesLiver DiseasesEndoplasmic Reticulum StressHumansNLR Family, Pyrin Domain-Containing 3 ProteinInflammasomesNLR Family, Pyrin Domain-Containing 3 Proteinendoplasmic reticulum stresshepatic ischemia–reperfusionhepatotoxicityliver injuryNLRP3 inflammasomenonalcoholic fatty liver disease

Identifiers

PMID35408890
PMCPMC8998408
OpenAlexW4220872525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.