ArticleInternational journal of molecular sciences2022
Toward a Treatment of Cancer: Design and In Vitro/In Vivo Evaluation of Uncharged Pyrazoline Derivatives as a Series of Novel SHP2 Inhibitors.
Jiajia Dai, Yiting Zhang, Yanan Gao, Xiaoyi Bai, Fang Liu, Shuo Li, Yanyan Yu, Wenpeng Hu, Ting Shi, Dayong Shi and 1 more
Open access · goldAbstract read
In one paragraphArticle in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors at 2 institutions in 1 country.
Jiajia DaiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Yiting ZhangState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Yanan GaoState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Xiaoyi BaiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Fang LiuState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Shuo LiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Yanyan YuState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Wenpeng HuState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Ting ShiCollege of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, China.ORCID 0000-0003-1394-3000 Dayong ShiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.
Xiangqian LiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266200, China.ORCID 0000-0002-5807-5633 Shandong University · CNShandong University of Science and Technology · CN
Funding
Fundamental Research Fund of Shandong University 2020GN033Joint fund of Shandong Natural Science Foundation ZR2021LSW013National Natural Science Foundation of China 82003787National Natural Science Foundation of China 82104029Natural Science Foundation of Shandong Province ZR2020QH364Qingdao Science and Technology Benefit People Demonstration Guide Special Project 20-3-4-20-nsh
6 · The paper itselfAbstract
Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) is a non-receptor protein tyrosine phosphatase (PTP) encoded by the
Indexed as
Antineoplastic AgentsNeoplasmsCatalytic DomainEnzyme InhibitorsHCT116 CellsHumansProtein Tyrosine Phosphatase, Non-Receptor Type 11Signal TransductionAntineoplastic AgentsEnzyme InhibitorsProtein Tyrosine Phosphatase, Non-Receptor Type 11anti-tumorapoptosisinhibitorSHP2toxicity
Identifiers
PMID35408869
PMCPMC8998978
OpenAlexW4223504308
What OpenQuestion holds
Textmetadata
LicenceCC BY
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