Evidence map›Paper›PMID 35408844›Full record

ReviewInternational journal of molecular sciences2022

Progress in Bioengineering Strategies for Heart Regenerative Medicine.

Timm Häneke, Makoto Sahara

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  12. Recent Advances in Generation of In Vitro Cardiac Organoids.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Timm HänekeDepartment of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.
Makoto SaharaDepartment of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0002-6281-5454
Karolinska Institutet · SE

Funding

Swedish Heart-Lung Foundation 20190380Swedish Research Council 2019-01359
6 · The paper itself

Abstract

The human heart has the least regenerative capabilities among tissues and organs, and heart disease continues to be a leading cause of mortality in the industrialized world with insufficient therapeutic options and poor prognosis. Therefore, developing new therapeutic strategies for heart regeneration is a major goal in modern cardiac biology and medicine. Recent advances in stem cell biology and biotechnologies such as human pluripotent stem cells (hPSCs) and cardiac tissue engineering hold great promise for opening novel paths to heart regeneration and repair for heart disease, although these areas are still in their infancy. In this review, we summarize and discuss the recent progress in cardiac tissue engineering strategies, highlighting stem cell engineering and cardiomyocyte maturation, development of novel functional biomaterials and biofabrication tools, and their therapeutic applications involving drug discovery, disease modeling, and regenerative medicine for heart disease.

Indexed as

Heart DiseasesPluripotent Stem CellsBioengineeringHumansMyocytes, CardiacRegenerative MedicineTissue Engineeringbiofabricationbiomaterialbioprintingcardiac tissue engineeringcardiomyocyte maturationcell therapyheart diseaseregenerative medicinestem cell biology

Identifiers

PMID35408844
PMCPMC8998628
OpenAlexW4223604018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.