Evidence map›Paper›PMID 35408695›Full record

ArticleMolecules (Basel, Switzerland)2022

Activated Carbon/Pectin Composite Enterosorbent for Human Protection from Intoxication with Xenobiotics Pb(II) and Sodium Diclofenac.

Jakpar Jandosov, Mo Alavijeh, Shynggyskhan Sultakhan, Alzhan Baimenov, Maria Bernardo, Zuriyadda Sakipova, Seytkhan Azat, Svitlana Lyubchyk, Nurzhamal Zhylybayeva, Gulmira Naurzbayeva and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
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  4. Synthesis and Study of SrTiOMolecules (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Jakpar JandosovSchool of Pharmacy, Asfendiyarov Kazakh National Medical University, 94, Tole Bi Street, Almaty 050000, Kazakhstan.
Mo AlavijehPharmidex Pharmaceutical Services, 14, Hanover Street, London W1S 1YH, UK.ORCID 0000-0002-2136-8344
Shynggyskhan SultakhanInstitute of Combustion Problems, 172, Bogenbay Batyr Street, Almaty 050000, Kazakhstan.ORCID 0000-0003-2195-755X
Alzhan BaimenovChemistry Division, Al-Farabi Kazakh National University, 71, Al-Farabi Avenue, Almaty 050040, Kazakhstan.ORCID 0000-0002-6509-2087
Maria BernardoLAQV/REQUIMTE, Departamento de Química (DQ), Faculdade de Ciências e Tecnologia (FCT), Universidade Nova de Lisboa (UNL), 2829-516 Caparica, Portugal.ORCID 0000-0002-5823-6636
Zuriyadda SakipovaSchool of Pharmacy, Asfendiyarov Kazakh National Medical University, 94, Tole Bi Street, Almaty 050000, Kazakhstan.
Seytkhan AzatChemistry Division, Al-Farabi Kazakh National University, 71, Al-Farabi Avenue, Almaty 050040, Kazakhstan.ORCID 0000-0002-9705-7438
Svitlana LyubchykLAQV/REQUIMTE, Departamento de Química (DQ), Faculdade de Ciências e Tecnologia (FCT), Universidade Nova de Lisboa (UNL), 2829-516 Caparica, Portugal.
Nurzhamal ZhylybayevaChemistry Division, Al-Farabi Kazakh National University, 71, Al-Farabi Avenue, Almaty 050040, Kazakhstan.ORCID 0000-0001-8047-916X
Gulmira NaurzbayevaInstitute of Combustion Problems, 172, Bogenbay Batyr Street, Almaty 050000, Kazakhstan.
Zulkhair MansurovInstitute of Combustion Problems, 172, Bogenbay Batyr Street, Almaty 050000, Kazakhstan.
Sergey MikhalovskyANAMAD Ltd., Sussex Innovation Centre Science Park Square, Falmer, Brighton BN1 9SB, UK.
Dmitriy BerilloSchool of Pharmacy, Asfendiyarov Kazakh National Medical University, 94, Tole Bi Street, Almaty 050000, Kazakhstan.ORCID 0000-0003-2534-9367
Al-Farabi Kazakh National University · KZKazakh National Medical University · KZRede de Química e Tecnologia · PTNational Academy of Sciences of Ukraine · UAPharmidex (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of enterosorbents-materials which can be administered orally and eliminate toxic substances from the gastrointestinal tract (GIT) by sorption-offers an attractive complementary protection of humans against acute and chronic poisoning. In this study, we report the results of developing a microgranulated binary biomedical preparation for oral use. It was designed with a core-shell structure based on pectin with low degree of esterification as the core, and nanoporous activated carbon produced from rice husk, AC-RH, as the shell, designated as AC-RH@pectin. The adsorption properties of the synthesized materials were studied in aqueous solutions for the removal of lead (II) nitrate as a representative of toxic polyvalent metals and sodium diclofenac as an example of a medicinal drug. The composite enterosorbent demonstrated high adsorption capacity for both adsorbates studied. Adsorption kinetics of lead and diclofenac adsorption by AC-RH, pectin, and AC-RH@pectin, fitted well a pseudo-second-order model. According to the Langmuir adsorption isotherm model, the best fitted isotherm model, the maximum adsorption capacity, q

Indexed as

CharcoalWater Pollutants, ChemicalAdsorptionDiclofenacHumansHydrogen-Ion ConcentrationKineticsLeadPectinsXenobioticsCharcoalDiclofenacLeadPectinsWater Pollutants, ChemicalXenobioticsdiclofenac adsorptionenterosorbentlead adsorptionpectinporous carbon

Identifiers

PMID35408695
PMCPMC9000640
OpenAlexW4223565917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.