Evidence map›Paper›PMID 35408672›Full record

ReviewMolecules (Basel, Switzerland)2022

Phytotherapeutic Approaches to the Prevention of Age-Related Changes and the Extension of Active Longevity.

Olga Babich, Viktoria Larina, Svetlana Ivanova, Andrei Tarasov, Maria Povydysh, Anastasiya Orlova, Jovana Strugar, Stanislav Sukhikh

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Olga BabichInstitute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, Kaliningrad 236016, Russia.ORCID 0000-0002-4921-8997
Viktoria LarinaInstitute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, Kaliningrad 236016, Russia.
Svetlana IvanovaNatural Nutraceutical Biotesting Laboratory, Kemerovo State University, Krasnaya Street 6, Kemerovo 650043, Russia.ORCID 0000-0002-1252-9572
Andrei TarasovDepartment of Pediatrics and Preventive Medicine, Medical Institute, Immanuel Kant Baltic Federal University, 14 A. Nevskogo ul., Kaliningrad 236016, Russia.ORCID 0000-0001-5749-1216
Maria PovydyshDepartment of Biochemistry, Saint Petersburg State Chemical Pharmaceutical University, Professora Popova 14A, Saint Petersburg 197376, Russia.
Anastasiya OrlovaDepartment of Pharmacognosy, Saint Petersburg State Chemical Pharmaceutical University, Professora Popova 14A, Saint Petersburg 197376, Russia.
Jovana StrugarDepartment of Pharmacognosy, Saint Petersburg State Chemical Pharmaceutical University, Professora Popova 14A, Saint Petersburg 197376, Russia.
Stanislav SukhikhInstitute of Living Systems, Immanuel Kant Baltic Federal University, A. Nevskogo Street 14, Kaliningrad 236016, Russia.
Immanuel Kant Baltic Federal University · RUSaint - Petersburg State Chemical Pharmaceutical Academy · RUKemerovo State University · RU

Funding

Russian Science Foundation 21-76-10055
6 · The paper itself

Abstract

Maintaining quality of life with an increase in life expectancy is considered one of the global problems of our time. This review explores the possibility of using natural plant compounds with antioxidant, anti-inflammatory, anti-glycation, and anti-neurodegenerative properties to slow down the onset of age-related changes. Age-related changes such as a decrease in mental abilities, the development of inflammatory processes, and increased risk of developing type 2 diabetes have a significant impact on maintaining quality of life. Herbal preparations can play an essential role in preventing and treating neurodegenerative diseases that accompany age-related changes, including Alzheimer's and Parkinson's diseases. Medicinal plants have known sedative, muscle relaxant, neuroprotective, nootropic, and antiparkinsonian properties. The secondary metabolites, mainly polyphenolic compounds, are valuable substances for the development of new anti-inflammatory and hypoglycemic agents. Understanding how mixtures of plants and their biologically active substances work together to achieve a specific biological effect can help develop targeted drugs to prevent diseases associated with aging and age-related changes. Understanding the mechanisms of the biological activity of plant complexes and mixtures determines the prospects for using metabolomic and biochemical methods to prolong active longevity.

Indexed as

Diabetes Mellitus, Type 2Plants, MedicinalAnti-Inflammatory AgentsHumansLongevityQuality of LifeAnti-Inflammatory Agentsaging of the human bodyanti-glycationanti-inflammatoryanti-neurodegenerative propertiesantioxidantmedicinal plants

Identifiers

PMID35408672
PMCPMC9000830
OpenAlexW4221089880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.