Evidence map›Paper›PMID 35408669›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Hemostatic Activity of New Amide Derivatives.

Lukasz Banach, Lukasz Janczewski, Jakub Kajdanek, Katarzyna Milowska, Joanna Kolodziejczyk-Czepas, Grzegorz Galita, Wioletta Rozpedek-Kaminska, Ewa Kucharska, Ireneusz Majsterek, Beata Kolesinska

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Lukasz BanachFaculty of Chemistry, Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.
Lukasz JanczewskiFaculty of Chemistry, Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.ORCID 0000-0003-4689-1622
Jakub KajdanekDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Katarzyna MilowskaDepartment of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-4050-2756
Joanna Kolodziejczyk-CzepasDepartment of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0001-8849-1067
Grzegorz GalitaDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-1559-2796
Wioletta Rozpedek-KaminskaDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0001-9206-1203
Ewa KucharskaDepartment of Gerontology, Geriatrics and Social Work, Jesuit University Ignatianum in Cracow, Kopernika 26, 31-501 Krakow, Poland.
Ireneusz MajsterekDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 90-419 Lodz, Poland.
Beata KolesinskaFaculty of Chemistry, Institute of Organic Chemistry, Lodz University of Technology, Zeromskiego 116, 90-924 Lodz, Poland.ORCID 0000-0002-4581-947X
Lodz University of Technology · PLMedical University of Lodz · PLUniversity of Łódź · PLAkademia Ignatianum w Krakowie · PL

Funding

National Centre for Research and Development POIR.04.01.02-00-0004/17
6 · The paper itself

Abstract

Eight dipeptides containing antifibrinolytic agents (tranexamic acid, aminocaproic acid, 4-(aminomethyl)benzoic acid, and glycine-natural amino acids) were synthesized in a three-step process with good or very good yields. DMT/NMM/TsO

Indexed as

HemostaticsAmidesDipeptidesHemolysisHemostasisHumansPartial Thromboplastin TimeProthrombin TimeAmidesDipeptidesHemostatics4-(aminomethyl)benzoic acidaminocaproic acidantifibrinolytic agentshemostasislysine analogspeptidestranexamic acid

Identifiers

PMID35408669
PMCPMC9000710
OpenAlexW4221057114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.