Evidence map›Paper›PMID 35408554›Full record

ArticleMolecules (Basel, Switzerland)2022

Tania Hernández-Jiménez, Guillermina Ferro-Flores, Enrique Morales-Ávila, Keila Isaac-Olivé, Blanca Ocampo-García, Liliana Aranda-Lara, Clara Santos-Cuevas, Myrna Luna-Gutiérrez, Laura De Nardo, Antonio Rosato and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Radiolabeling lipoproteins to study and manage disease.European journal of nuclear medicine and molecular imaging · 2025
    Review
  4. Review
  5. Synthesis and Evaluation ofInternational journal of molecular sciences · 2023
    Article
  6. Metal-Based Radiopharmaceuticals in Inorganic Chemistry.Molecules (Basel, Switzerland) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Tania Hernández-JiménezDepartment of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico.
Guillermina Ferro-FloresDepartment of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico.ORCID 0000-0003-0296-7605
Enrique Morales-ÁvilaFaculty of Chemistry, Universidad Autónoma del Estado de México, Toluca 50180, Mexico.ORCID 0000-0001-8471-6791
Keila Isaac-OlivéFaculty of Medicine, Universidad Autónoma del Estado de México, Toluca 50180, Mexico.
Blanca Ocampo-GarcíaDepartment of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico.ORCID 0000-0002-5831-8412
Liliana Aranda-LaraFaculty of Medicine, Universidad Autónoma del Estado de México, Toluca 50180, Mexico.
Clara Santos-CuevasDepartment of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico.ORCID 0000-0001-5903-1598
Myrna Luna-GutiérrezDepartment of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico.ORCID 0000-0002-4082-3816
Laura De NardoDepartment of Physics and Astronomy, University of Padua, 35131 Padova, Italy.ORCID 0000-0002-0061-370X
Antonio RosatoDepartment of Surgery, Oncology and Gastroenterology, University of Padova, 35138 Padova, Italy.ORCID 0000-0002-5263-8386
Laura Meléndez-AlafortVeneto Institute of Oncology IOV-IRCCS, 35138 Padova, Italy.ORCID 0000-0003-0701-3616
Instituto Nacional de Investigaciones Nucleares · MXUniversidad Autónoma del Estado de México · MXUniversity of Padua · ITIstituto Oncologico Veneto · IT

Funding

Consejo Nacional de Ciencia y Tecnología CB2017-2018-A1-S-36841
6 · The paper itself

Abstract

Actinium-225 and other alpha-particle-emitting radionuclides have shown high potential for cancer treatment. Reconstituted high-density lipoproteins (rHDL) specifically recognize the scavenger receptor B type I (SR-BI) overexpressed in several types of cancer cells. Furthermore, after rHDL-SR-BI recognition, the rHDL content is injected into the cell cytoplasm. This research aimed to prepare a targeted

Indexed as

NanoparticlesNeoplasmsAlpha ParticlesAnimalsLipoproteins, HDLMiceReceptors, ScavengerLipoproteins, HDLReceptors, Scavenger225Ac-rHDLactinium-225reconstituted high-density lipoproteinsscavenger receptor B type Itargeted alpha-particle therapy

Identifiers

PMID35408554
PMCPMC9000893
OpenAlexW4220966237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.