Evidence map›Paper›PMID 35408532›Full record

ArticleMolecules (Basel, Switzerland)2022

Inhibition of Aldose Reductase by Ginsenoside Derivatives via a Specific Structure Activity Relationship with Kinetics Mechanism and Molecular Docking Study.

Md Yousof Ali, Sumera Zaib, Susoma Jannat, Imtiaz Khan, M Mizanur Rahman, Seong Kyu Park, Mun Seog Chang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Chemical Composition of theAntibiotics (Basel, Switzerland) · 2023
    Article
  7. Ginsenosides on stem cells fate specification-a novel perspective.Frontiers in cell and developmental biology · 2023
    Review
  8. 6-Formyl Umbelliferone, a Furanocoumarin fromMolecules (Basel, Switzerland) · 2022
    Article
  9. Linearolactone Induces Necrotic-like Death inPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Md Yousof AliDepartment of Physiology and Pharmacology, Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0003-1488-5711
Sumera ZaibDepartment of Biochemistry, Faculty of Life Sciences, University of Central Punjab, Lahore 54590, Pakistan.
Susoma JannatDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB T2N 1N4, Canada.
Imtiaz KhanDepartment of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
M Mizanur RahmanDepartment of Biotechnology and Genetic Engineering, Faculty of Biological Science, Islamic University, Kushtia 7003, Bangladesh.
Seong Kyu ParkDepartment of Prescriptionology, College of Korean Medicine, Kyung Hee University, 26 Kyunghee dae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Mun Seog ChangDepartment of Prescriptionology, College of Korean Medicine, Kyung Hee University, 26 Kyunghee dae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Kyung Hee University · KRUniversity of Calgary · CAIslamic University · BDUniversity of Central Punjab · PKUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This present work is designed to evaluate the anti-diabetic potential of 22 ginsenosides via the inhibition against rat lens aldose reductase (RLAR), and human recombinant aldose reductase (HRAR), using

Indexed as

Aldehyde ReductaseGinsenosidesAnimalsKineticsMolecular Docking SimulationRatsSorbitolStructure-Activity RelationshipAldehyde ReductaseGinsenosidesSorbitolaldose reductasediabetic complicationenzyme kineticsginsenosidesmolecular dockingsorbitol accumulation

Identifiers

PMID35408532
PMCPMC9000482
OpenAlexW4220733786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.