Evidence map›Paper›PMID 35408473›Full record

ArticleMolecules (Basel, Switzerland)2022

A Comparative Study between Conventional and Advanced Extraction Techniques: Pharmaceutical and Cosmetic Properties of Plant Extracts.

Ezzouhra El Maaiden, Sarah Bouzroud, Boubker Nasser, Khadija Moustaid, Ayoub El Mouttaqi, Mohamed Ibourki, Hassan Boukcim, Abdelaziz Hirich, Lamfeddal Kouisni, Youssef El Kharrassi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Review
  3. A deep dive into herbal extraction: Techniques, trends, and technological advancements.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2026
    Article
  4. Article
  5. Piperine: From Green Extraction to Clinical Translation-A Review.Drug design, development and therapy · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Extraction of Bioactive Compounds FromInternational journal of food science · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Natural products as a source of Coronavirus entry inhibitors.Frontiers in cellular and infection microbiology · 2024
    Review
  17. Review
  18. Review
  19. Article
  20. Ultrasound-Assisted Extraction of Isoquercetin fromAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ezzouhra El MaaidenAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Sarah BouzroudAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.ORCID 0000-0001-9430-2242
Boubker NasserLaboratory of Biochemistry, Neurosciences, Natural Resources and Environment, Hassan First University of Settat, BP 577, Settat 26000, Morocco.
Khadija MoustaidLaboratory of Applied Chemistry and Environment, Hassan First University of Settat, BP 577, Settat 26000, Morocco.
Ayoub El MouttaqiAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Mohamed IbourkiAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Hassan BoukcimAgroBioSciences Department (AgBS), Mohammed VI Polytechnic University (UM6P), Lot 660, Hay Moulay Rachid, Benguerir 43150, Morocco.
Abdelaziz HirichAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Lamfeddal KouisniAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Youssef El KharrassiAfrican Sustainable Agriculture Research Institute (ASARI), Mohammed VI Polytechnic University (UM6P), Laâyoune 70000, Morocco.
Université Mohammed VI Polytechnique · MAUniversité Hassan 1er · MA

Funding

OCP Phosboucraâ Foundation PR005
6 · The paper itself

Abstract

This study aimed to compare the influence of extraction methods on the pharmaceutical and cosmetic properties of medicinal and aromatic plants (MAPs). For this purpose, the dried plant materials were extracted using advanced (microwave (MAE), ultrasonic (UAE), and homogenizer (HAE) assisted extractions) and conventional techniques (maceration, percolation, decoction, infusion, and Soxhlet). The tyrosinase, elastase, α-amylase, butyryl, and acetylcholinesterase inhibition were tested by using L-3,4 dihydroxy-phenylalanine, N-Succinyl-Ala-Ala-p-nitroanilide, butyryl, and acetylcholine as respective substrates. Antioxidant activities were studied by ABTS, DPPH, and FRAP. In terms of extraction yield, advanced extraction techniques showed the highest values (MAE > UAE > HAE). Chemical profiles were dependent on the phenolic compounds tested, whereas the antioxidant activities were always higher, mainly in infusion and decoction as a conventional technique. In relation to the pharmaceutical and cosmetic properties, the highest inhibitory activities against α-amylase and acetylcholinesterase were observed for Soxhlet and macerated extracts, whereas the highest activity against tyrosinase was obtained with MAE > maceration > Soxhlet. Elastase and butyrylcholinesterase inhibitory activities were in the order of Soxhlet > maceration > percolation, with no activities recorded for the other tested methods. In conclusion, advanced methods afford an extract with high yield, while conventional methods might be an adequate approach for minimal changes in the biological properties of the extract.

Indexed as

Plant ExtractsPlants, MedicinalAcetylcholinesterasealpha-AmylasesAntioxidantsButyrylcholinesteraseMonophenol MonooxygenasePancreatic ElastaseAcetylcholinesterasealpha-AmylasesAntioxidantsButyrylcholinesteraseMonophenol MonooxygenasePancreatic ElastasePlant Extractsadvanced extractionbioactive compoundsconventional extractionenzyme inhibitionmicrowave-assisted extractionoxidative stress

Identifiers

PMID35408473
PMCPMC9000874
OpenAlexW4220879118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.