SynthesisSensors (Basel, Switzerland)2022
A Systematic Review on Healthcare Artificial Intelligent Conversational Agents for Chronic Conditions.
Synthesis in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of chatbot interventions in individuals for hypertension management: a systematic review and narrative synthesis.Frontiers in digital health · 2026Pooled it
- Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review.Journal of medical Internet research · 2025Pooled it
- A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness.Annals of medicine · 2024Pooled it
- Chatbot Artificial Intelligence for Genetic Cancer Risk Assessment and Counseling: A Systematic Review and Meta-Analysis.JCO clinical cancer informatics · 2023Pooled it
- Multilingual Voice AI for Postoperative Cataract Follow-Up in Turkish Speaking Patients in the United Kingdom: Patient and Public Involvement Focus Group Study.JMIR formative research · 2026Article
- Evolution of Chatbots as an Educational and Supportive Digital Intervention for Family Caregivers of People With Dementia: Protocol for a Systematic Integrative Review.JMIR research protocols · 2026Article
- Moral injury in a VUCA healthcare environment: ethical complexities and professional challenges for medical teams.BMC health services research · 2026Article
- Article
- Effectiveness of virtual nurse interventions in chronic disease self-management: a systematic review of randomized controlled trials.BMC nursing · 2026Article
- Review of Artificial Intelligence for Clinical Use in Alzheimer's Disease and Related Dementias.Seminars in neurology · 2026Review
- "Your Digital Doctor Will Now See You": A Narrative Review of VR and AI Technology in Chronic Illness Management.Healthcare (Basel, Switzerland) · 2026Review
- Artificial intelligence applications in oxaliplatin-based chemotherapy for colon cancer: advancing prognosis, toxicity prediction, and dose personalization.Frontiers in pharmacology · 2026Review
- Applications of Artificial Intelligence Technologies in Nursing for Noncommunicable Chronic Diseases: A Scoping Review.Journal of nursing management · 2026Article
- Article
- Determining the Feasibility and Usability of a Co-Designed Culturally Appropriate Conversational Agent (DESI-Heart) to Support Self-Care in People With Cardiovascular Diseases: Protocol for a Single-Arm Pilot Trial.JMIR research protocols · 2025Article
- Examining the Acceptance and Use of AI-Based Assistive Technology Among University Students with Visual Disability: The Moderating Role of Physical Self-Esteem.Bioengineering (Basel, Switzerland) · 2025Article
- Detecting Artificial Intelligence-Generated Versus Human-Written Medical Student Essays: Semirandomized Controlled Study.JMIR medical education · 2025Article
- Exploring the Role of Voice Assistants in Managing Noncommunicable Diseases: A Systematic Review on Clinical, Behavioral Outcomes, Quality of Life, and User Experiences.Healthcare (Basel, Switzerland) · 2025Review
- Review
- Feasibility and Preliminary Behavioral and Clinical Efficacy of a Diabetes Education Chatbot Pilot Among Adults With Type 2 Diabetes.Journal of diabetes science and technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper reviews different types of conversational agents used in health care for chronic conditions, examining their underlying communication technology, evaluation measures, and AI methods. A systematic search was performed in February 2021 on PubMed Medline, EMBASE, PsycINFO, CINAHL, Web of Science, and ACM Digital Library. Studies were included if they focused on consumers, caregivers, or healthcare professionals in the prevention, treatment, or rehabilitation of chronic diseases, involved conversational agents, and tested the system with human users. The search retrieved 1087 articles. Twenty-six studies met the inclusion criteria. Out of 26 conversational agents (CAs), 16 were chatbots, seven were embodied conversational agents (ECA), one was a conversational agent in a robot, and another was a relational agent. One agent was not specified. Based on this review, the overall acceptance of CAs by users for the self-management of their chronic conditions is promising. Users' feedback shows helpfulness, satisfaction, and ease of use in more than half of included studies. Although many users in the studies appear to feel more comfortable with CAs, there is still a lack of reliable and comparable evidence to determine the efficacy of AI-enabled CAs for chronic health conditions due to the insufficient reporting of technical implementation details.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.