ArticleMaterials (Basel, Switzerland)2022
Highly Photostable Carbon Dots from Citric Acid for Bioimaging.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Optimized melanin production from marine-associated Bacillus sp. EGY7 as a sustainable precursor of carbon dots for biomedical applications.Bioresources and bioprocessing · 2026Article
- Carbon Nanodot-enabled Fluorescent Nerve Conduits for Peripheral Nerve Repair: A Systematic Review of Translational Readiness.Plastic and reconstructive surgery. Global open · 2026Article
- Design, Synthesis, and Characterization ofACS omega · 2026Article
- Development of AS1411 aptamer-conjugated chitosan-carbon dot nanocarriers for targeted drug delivery and fluorescent imaging in breast cancer therapy.Journal of biological engineering · 2026Article
- One-Step Microwave-Assisted Fabrication of Carbon Dots as Efficient Fluorescent Chemosensors for HgSensors (Basel, Switzerland) · 2025Article
- Bioimaging application and growth-promoting behavior of Auxin-derived carbon dots on cancer cell and seed performance.Journal of biological engineering · 2025Article
- Antioxidant activity and in vitro fluorescence imaging application of N-, O- functionalized carbon dots.Scientific reports · 2025Article
- Facile synthesis of long-wavelength dual-emissive carbon dots for multifunctional use in pH sensing, vitamin BMikrochimica acta · 2025Article
- Manifestation of Donor-Acceptor Properties of N-Doped Polymer Carbon Dots During Hydrogen Bonds Formation in Different Solvents.Polymers · 2024Article
- Mandarin Peels-Derived Carbon Dots: A Multifaceted Fluorescent Probe for Cu(II) Detection in Tap and Drinking Water Samples.Nanomaterials (Basel, Switzerland) · 2024Article
- Microporous Fluorescent Poly(D,L-lactide) Acid-Carbon Nanodot Scaffolds for Bone Tissue Engineering Applications.Materials (Basel, Switzerland) · 2024Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Bioimaging supported by nanoparticles requires low cost, highly emissive and photostable systems with low cytotoxicity. Carbon dots (C-dots) offer a possible solution, even if controlling their properties is not always straightforward, not to mention their potentially simple synthesis and the fact that they do not exhibit long-term photostability in general. In the present work, we synthesized two C-dots starting from citric acid and tris (hydroxymethyl)-aminomethane (tris) or arginine methyl ester dihydrochloride. Cellular uptake and bioimaging were tested in vitro using murine neuroblastoma and ovine fibroblast cells. The C-dots are highly biocompatible, and after 24 h of incubation with the cells, 100% viability was still observed. Furthermore, the C-dots synthesized using tris have an average dimension of 2 nm, a quantum yield of 37%, high photostability and a zeta potential (ζ) around -12 mV. These properties favor cellular uptake without damaging cells and allow for very effective bioimaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.