Evidence map›Paper›PMID 35407533›Full record

ArticleJournal of clinical medicine2022

Clinical Characteristics of Anti-TIF-1γ Antibody-Positive Dermatomyositis Associated with Malignancy.

Yumi Harada, Masaki Tominaga, Eriko Iitoh, Shinjiro Kaieda, Takuma Koga, Kiminori Fujimoto, Tomonori Chikasue, Hitoshi Obara, Tatsuyuki Kakuma, Hiroaki Ida and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Sequence Alignment betweenJournal of personalized medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. A Case Report of Anti-TIF1-Case reports in rheumatology · 2023
    Article
  13. Review
  14. Article
  15. A Rare Case of Anti-TIF-1γ Antibody Positive Dermatomyositis in Adulthood.Journal of investigative medicine high impact case reports
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yumi HaradaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Masaki TominagaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.ORCID 0000-0002-6972-1338
Eriko IitohDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Shinjiro KaiedaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Takuma KogaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Kiminori FujimotoDepartment of Radiology, Center for Diagnostic Imaging, Kurume University School of Medicine, Kurume 830-0011, Japan.
Tomonori ChikasueDepartment of Radiology, Center for Diagnostic Imaging, Kurume University School of Medicine, Kurume 830-0011, Japan.
Hitoshi ObaraBiostatistics Center, Kurume University, Kurume 830-0011, Japan.
Tatsuyuki KakumaBiostatistics Center, Kurume University, Kurume 830-0011, Japan.
Hiroaki IdaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.ORCID 0000-0003-0295-0301
Tomotaka KawayamaDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Tomoaki HoshinoDivision of Respirology, Department of Medicine, Neurology and Rheumatology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We retrospectively analyzed the clinical and laboratory data of patients diagnosed with anti-transcriptional intermediary factor 1 (TIF-1γ) antibody-positive polymyositis (PM)/dermatomyositis (DM) to clarify the characteristics of this disease. We identified 14 patients with TIF-1γ antibody-positive DM (TIF-1γ DM), 47 with anti-aminoacyl-tRNA synthetase antibody (ARS)-positive PM/DM, and 24 with anti-melanoma differentiation-associated gene 5 antibody (MDA-5)-positive PM/DM treated at the Kurume University Hospital between 2002 and 2020. Patients with TIF-1γ DM were significantly older than the other two groups. Nine patients with TIF-1γ DM were female, thirteen patients had DM, and one had clinically amyopathic DM. Primary malignant lesions were lung (3), uterus (2), colon (2), breast (2), ovary (1), lymphoma (1), and unknown (2). Cutaneous manifestation and dysphagia were the most common symptoms in TIF-1γ DM. Erythema (9/14), the V-neck sign (8/14), heliotrope (9/14), and nailfold telangiectasia (14/14) were significantly more common in TIF-1γ DM. Furthermore, no patients with TIF-1γ DM had interstitial lung abnormality on high-resolution CT. In patients with TIF-1γ DM, the frequency of dysphagia and unusual erythema, particularly that which spreads from the trunk, and nailfold telangiectasia, were characteristic findings. In most patients with TIF-1γ DM, it is necessary to administer other immunosuppressive drugs along with glucocorticoids.

Indexed as

anti-aminoacyl tRNA synthetase (ARS) antibodyanti-melanoma differentiation-associated gene 5 (MDA-5) antibodyanti-transcriptional intermediary factor 1 (TIF-1γ) antibodydermatomyositis (DM)skin manifestation

Identifiers

PMID35407533
PMCPMC8999723
OpenAlexW4220707093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.