Evidence map›Paper›PMID 35407424›Full record

ArticleJournal of clinical medicine2022

A Novel Quantitative Parameter for Static Myocardial Computed Tomography: Myocardial Perfusion Ratio to the Aorta.

Takanori Kouchi, Yuki Tanabe, Takumasa Takemoto, Kazuki Yoshida, Yuta Yamamoto, Shigehiro Miyazaki, Naoki Fukuyama, Hikaru Nishiyama, Shinji Inaba, Naoto Kawaguchi and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Takanori KouchiDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Yuki TanabeDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Takumasa TakemotoDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Kazuki YoshidaDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Yuta YamamotoDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Shigehiro MiyazakiDepartment of Cardiology, Pulmonology, Hypertension and Nephrology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Naoki FukuyamaDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Hikaru NishiyamaDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Shinji InabaDepartment of Cardiology, Pulmonology, Hypertension and Nephrology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Naoto KawaguchiDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Tomoyuki KidoDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.
Osamu YamaguchiDepartment of Cardiology, Pulmonology, Hypertension and Nephrology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.ORCID 0000-0002-7461-369X
Teruhito KidoDepartment of Radiology, Graduate School of Medicine, Ehime University, Shitsukawa, Toon 791-0295, Japan.ORCID 0000-0002-7645-4311

Funding

Kaken Pharmaceutical (Japan) JP20K16760
6 · The paper itself

Abstract

We evaluated the feasibility of myocardial perfusion ratio to the aorta (MPR) in static computed tomography perfusion (CTP) for detecting myocardial perfusion abnormalities assessed by single-photon emission computed tomography (SPECT). Twenty-five patients with suspected coronary artery disease who underwent dynamic CTP and SPECT were retrospectively evaluated. CTP images scanned at a sub-optimal phase for detecting myocardial perfusion abnormalities were selected from dynamic CTP images and used as static CTP images in the present study. The diagnostic accuracy of MPR derived from static CTP was compared to those of visual assessment and conventional quantitative parameters such as myocardial CT attenuation (HU) and transmural perfusion ratio (TPR). The area under the curve of MPR (0.84; 95% confidence interval [CI], 0.76−0.90) was significantly higher than those of myocardial CT attenuation (0.73; 95% CI, 0.65−0.79) and TPR (0.76; 95% CI, 0.67−0.83) (p < 0.05). Sensitivity and specificity were 67% (95% CI, 54−77%) and 90% (95% CI, 86−92%) for visual assessment, 51% (95% CI, 39−63%) and 86% (95% CI, 82−89%) for myocardial CT attenuation, 63% (95% CI, 51−74%) and 84% (95% CI, 80−88%) for TPR, and 78% (95% CI, 66−86%) and 84% (95% CI, 80−88%) for MPR, respectively. MPR showed higher diagnostic accuracy for detecting myocardial perfusion abnormality compared with myocardial CT attenuation and TPR.

Indexed as

computed tomographycomputed tomography perfusionmyocardial perfusion abnormality

Identifiers

PMID35407424
PMCPMC8999663

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.