ReviewJournal of clinical medicine2022
Prenatal Diagnosis and Postnatal Outcomes of Left Brachiocephalic Vein Abnormalities: Systematic Review.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Major Vessels of the Interclavicular Suprasternal Space: A Suprasternal Notch-Referenced Topographic Classification with Potential Procedural Relevance.Diagnostics (Basel, Switzerland) · 2026Article
- The Effects of Maternal Subclinical Hypothyroidism on Fetal Thymus Size: A Prospective Study.Diagnostics (Basel, Switzerland) · 2025Article
- Double innominate vein in a case with double aortic arch: a case report.Journal of cardiothoracic surgery · 2024Article
- Article
- Ventricular septal defect with uncommon three left brachiocephalic veins.European heart journal. Case reports · 2023Article
- Vascular ring: prenatal diagnosis and prognostic management based on sequential cross-sectional scanning by ultrasound.BMC pregnancy and childbirth · 2023Article
- Recent Advances in the Diagnosis and Management of Congenital Heart Defects.Journal of clinical medicine · 2022Article
- Case report of double superior vena cava and double odd vein with hypoplastic left brachiocephalic vein.The Journal of international medical research · 2022Article
- Severity and Extent of Lead-Related Venous Obstruction in More Than 3000 Patients Undergoing Transvenous Lead Extraction.Vascular health and risk management · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abnormalities of the left brachiocephalic vein (LBCVA) are rare and poorly studied prenatally. An association with congenital heart defects (CHD), extracardiac and genetic abnormalities was described. The aim of our study was to estimate the rate and summarize the available evidence concerning prenatal diagnosis, associated anomalies, and outcomes of these anomalies. A systematic literature review was carried out selecting studies reporting on prenatal diagnosis of LBCVA, including unpublished cases from our experience. Frequencies were pooled from cohort studies to calculate prenatal incidence. Pooled proportions were obtained from all the studies including rates of associated CHD, extracardiac or genetic abnormalities and neonatal outcomes. The search resulted in the selection of 16 studies with 311 cases of LBCVA, with an incidence of 0.4% from six cohort studies. CHD occurred in 235/311 (75.6%) fetuses: 23 (7.4%) were major in cases of double, retroesophageal or subaortic course and 212 (68.2%) were minor in cases of absence (always associated with a persistent left superior vena cava) or intrathymic course. Data on other associated outcomes were scarce showing rare extracardiac anomalies (3.5%), rare genetic abnormalities (RASopathies and microdeletions associated with the retroesophageal course), and neonatal outcomes favorable in most cases, particularly in intrathymic forms.
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