Evidence map›Paper›PMID 35407403›Full record

ArticleJournal of clinical medicine2022

Characteristics and Outcomes of Patients with Acute Coronary Syndrome and COVID-19.

Aleksandra Milovančev, Milovan Petrović, Višeslav Popadić, Tatjana Miljković, Slobodan Klašnja, Predrag Djuran, Aleksandra Ilić, Mila Kovačević, Anastazija Stojšić Milosavljević, Milica Brajković and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Aleksandra MilovančevFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.ORCID 0000-0002-4398-8093
Milovan PetrovićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Višeslav PopadićUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.ORCID 0000-0002-0992-7481
Tatjana MiljkovićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Slobodan KlašnjaUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.ORCID 0000-0002-6040-0183
Predrag DjuranUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
Aleksandra IlićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Mila KovačevićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Anastazija Stojšić MilosavljevićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Milica BrajkovićUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
Bogdan CrnokrakUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
Lidija MemonUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
Ana MilojevićUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
Zoran TodorovićUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.ORCID 0000-0001-8869-9976
Milenko ČankovićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Mirka Lukić ŠarkanovićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Snežana BjelićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Snežana TadićFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Aleksandar RedžekFaculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Marija ZdravkovićUniversity Hospital Medical Center Bežanijska Kosa, 11000 Belgrade, Serbia.
University of Novi Sad · RSUniversity Hospital Medical Center Bezanijska kosa · RSUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary syndrome (ACS) in patients with COVID-19 is triggered by various mechanisms and can significantly affect the patient’s further treatment and prognosis. The study aimed to investigate the characteristics, major complications, and predictors of mortality in COVID-19 patients with ACS. All consecutive patients hospitalized from 5 July 2020 to 5 May 2021 for ACS with confirmed SARS-Co-2 were prospectively enrolled and tracked for mortality until 5 June 2021. Data from the electronic records for age and diagnosis, matched non-COVID-19 and COVID-19 ACS group, were extracted and compared. Overall, 83 COVID-19 ACS patients, when compared to 166 non-COVID ACS patients, had significantly more prevalent comorbidities, unfavorable clinical characteristics on admission (acute heart failure 21.7% vs. 6.6%, p < 0.01) and higher rates of major complications, 33.7% vs. 16.8%, p < 0.01, and intrahospital 30-day mortality, 6.7% vs. 26.5%, p < 0.01. The strongest predictors of mortality were aortic regurgitation, HR 9.98, 95% CI 1.88; 52.98, p < 0.01, serum creatinine levels, HR 1.03, 95% CI 1.01; 1.04, p < 0.01, and respiratory failure therapy, HR 13.05, 95% CI 3.62; 47.01, p < 0.01. Concomitant ACS and COVID-19 is linked to underlying comorbidities, adverse presenting features, and poor outcomes. Urgent strategies are needed to improve the outcomes of these patients.

Indexed as

acute coronary syndromecoronavirusCOVID-19mortalitymyocardial infarction

Identifiers

PMID35407403
PMCPMC9000139
OpenAlexW4220801155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.