Evidence map›Paper›PMID 35407387›Full record

ArticleJournal of clinical medicine2022

Intravascular Lithotripsy for the Treatment of Stent Underexpansion: The Multicenter IVL-DRAGON Registry.

Wojciech Wańha, Mariusz Tomaniak, Piotr Wańczura, Jacek Bil, Rafał Januszek, Rafał Wolny, Maksymilian P Opolski, Łukasz Kuźma, Adam Janas, Tomasz Figatowski and 31 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06276114 (Comparison of Intravascular Coronary Lithotripsy and Excimer Laser Coronary Atherectomy for Severe Stent Underexpansion), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06276114 completednot on this map

Comparison of Intravascular Coronary Lithotripsy and Excimer Laser Coronary Atherectomy for Severe Stent Underexpansion: the Multicenter IVL- ELCA DRAGON Registry

Typeobservational_patient_registrySponsorMedical University of SilesiaRan2020 to 2023Enrolled121ConditionsCoronary Artery Calcification, Intravascular Lithotripsy, Excimer Laser-coronary Atherectomy, Stent RestenosisArmsStent Underexpansion
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Efficacy and Safety of Intravascular Lithotripsy in the Management of Underexpanded Stents: A Systematic Review and Meta-Analysis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Successful Intravascular Lithotripsy Within a Covered Coronary Stent.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  8. A Multicenter Retrospective Analysis of the Utility of Intravascular Lithotripsy in Underexpanded Stents.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Management of Stent Underexpansion and Aorto-ostial Lesions.Interventional cardiology (London, England) · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Intravascular lithotripsy for the treatment of inferior mesenteric artery in-stent restenosis.Journal of vascular surgery cases and innovative techniques · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors at 14 institutions in 2 countries.

Wojciech WańhaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0003-1220-9496
Mariusz Tomaniak1st Department of Cardiology, Medical University of Warsaw, 02-091 Warszawa, Poland.ORCID 0000-0001-8289-1393
Piotr WańczuraDepartment of Cardiology, The Ministry of Internal Affairs and Administration Hospital, 35-111 Rzeszów, Poland.
Jacek BilDepartment of Invasive Cardiology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.ORCID 0000-0002-8724-5611
Rafał JanuszekDepartment of Cardiology, Jagiellonian University Medical College, 31-008 Krakow, Poland.ORCID 0000-0002-6591-1919
Rafał WolnyDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.ORCID 0000-0001-9661-7563
Maksymilian P OpolskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Łukasz KuźmaDepartment of Invasive Cardiology, Medical University of Bialystok, 15-089 Bialystok, Poland.ORCID 0000-0002-4156-5695
Adam JanasFaculty of Medicine and Health Science, Andrzej Frycz Modrzewski Kraków University, 30-705 Krakow, Poland.ORCID 0000-0003-2360-7991
Tomasz FigatowskiFirst Department of Cardiology, Medical University of Gdansk, 80-210 Gdansk, Poland.ORCID 0000-0001-6120-5219
Paweł GąsiorDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0001-8564-7257
Marek MilewskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0001-5459-9125
Magda Roleder-DylewskaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.
Łukasz LewickiDepartment of Invasive Cardiology, University Center for Cardiology, 80-211 Gdansk, Poland.
Jan KulczyckiDepartment of Cardiology, Miedziowe Centrum Zdrowia, 59-300 Lubin, Poland.ORCID 0000-0002-6670-6044
Adrian WłodarczakDepartment of Cardiology, Miedziowe Centrum Zdrowia, 59-300 Lubin, Poland.ORCID 0000-0003-3104-7728
Brunon TomasiewiczCentre for Heart Disease, University Hospital, 50-558 Wroclaw, Poland.
Sylwia IwańczykDepartment of Cardiology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Jerzy SachaDepartment of Cardiology, University Hospital, Institute of Medical Sciences, University of Opole, 45-040 Opole, Poland.ORCID 0000-0001-7504-7506
Łukasz Koltowski1st Department of Cardiology, Medical University of Warsaw, 02-091 Warszawa, Poland.
Miłosz DziarmagaDepartment of Cardiology-Intensive Therapy and Internal Diseases, Poznan University of Medical Sciences, 60-355 Poznan, Poland.
Miłosz JaguszewskiFirst Department of Cardiology, Medical University of Gdansk, 80-210 Gdansk, Poland.
Paweł KraliszDepartment of Invasive Cardiology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Bartosz Olajossy1st Military Hospital in Lublin, 20-049 Lublin, Poland.
Grzegorz Sobieszek1st Military Hospital in Lublin, 20-049 Lublin, Poland.ORCID 0000-0003-1950-2804
Krzysztof DyrbuśThird Department of Cardiology, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0003-1323-1089
Mariusz ŁebekUpper Silesia Medical Centre, 40-635 Katowice, Poland.
Grzegorz SmolkaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.
Krzysztof ReczuchCentre for Heart Disease, University Hospital, 50-558 Wroclaw, Poland.ORCID 0000-0002-1699-739X
Robert J GilDepartment of Invasive Cardiology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.
Sławomir DobrzyckiDepartment of Invasive Cardiology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Piotr KwiatkowskiDepartment of Cardiology and Internal Diseases, Military Institute of Medicine, 04-141 Warsaw, Poland.
Marcin RogalaTerumo, 02-134 Warszawa, Poland.
Mariusz GąsiorThird Department of Cardiology, Medical University of Silesia, 40-055 Katowice, Poland.
Andrzej OchałaDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.
Janusz Kochman1st Department of Cardiology, Medical University of Warsaw, 02-091 Warszawa, Poland.
Adam WitkowskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Maciej LesiakDepartment of Cardiology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0003-2630-5016
Fabrizio D'AscenzoDivision of Cardiology, Department of Internal Medicine, Città della Salute e della Scienza, University of Turin, 10124 Turin, Italy.
Stanisław BartuśDepartment of Cardiology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Wojciech WojakowskiDepartment of Cardiology and Structural Heart Diseases, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0002-3681-5207
Medical University of Silesia · PLInstitute of Cardiology · PLMedical University of Białystok · PLMedical University of Warsaw · PLPoznan University of Medical Sciences · PL1 Military Clinical Hospital with Outpatient Clinic · PLGdańsk Medical University · PLJagiellonian University · PLPostgraduate School of Molecular Medicine · PLWroclaw Medical University · PLAndrzej Frycz Modrzewski Krakow University · PLUniversity of Opole · PLUniversity of Turin · ITWojskowy Instytut Medycyny Lotniczej · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whereas the efficacy and safety of intravascular lithotripsy (IVL) have been confirmed in de novo calcified coronary lesions, little is known about its utility in treating stent underexpansion. This study aimed to investigate the impact of IVL in treating stent underexpansion. Methods and Results: Consecutive patients with stent underexpansion treated with IVL entered the multicenter IVL-Dragon Registry. The procedural success (primary efficacy endpoint) was defined as a relative stent expansion >80%. Thirty days device-oriented composite endpoint (DOCE) (defined as a composite of cardiac death, target lesion revascularization, or target vessel myocardial infarction) was the secondary endpoint. A total of 62 patients were enrolled. The primary efficacy endpoint was achieved in 72.6% of patients. Both stent underexpansion 58.5% (47.5−69.7) vs. 11.4% (5.8−20.7), p < 0.001, and the stenotic area 82.6% (72.4−90.8) vs. 21.5% (11.1−37.2), p < 0.001, measured by quantitative coronary angiography improved significantly after IVL. Intravascular imaging confirmed increased stent expansion following IVL from 37.5% (16.0−66.0) to 86.0% (69.2−90.7), p < 0.001, by optical coherence tomography and from 57.0% (31.5−77.2) to 89.0% (85.0−92.0), p = 0.002, by intravascular ultrasound. Secondary endpoint occurred in one (1.6%) patient caused by cardiac death. There was no target lesion revascularization or target vessel myocardial infarction during the 30-day follow-up. Conclusions: In this real-life, largest-to-date analysis of IVL use to manage underexpanded stent, IVL proved to be an effective and safe method for facilitating stent expansion and increasing luminal gain.

Indexed as

calcified lesionsintravascular lithotripsypercutaneous coronary interventionstent underexpansion

Identifiers

PMID35407387
PMCPMC9000023
OpenAlexW4221001426

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.