ArticleNanomaterials (Basel, Switzerland)2022
Bio-Inspired Nanostructured Ti-6Al-4V Alloy: The Role of Two Alkaline Etchants and the Hydrothermal Processing Duration on Antibacterial Activity.
Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Preparation methods, mechano-bactericidal performance and mechanisms of Ti-based nanostructure arrays: A review.Discover nano · 2026Review
- Research Progress on Bioinspired Superhydrophobic Photothermal Anti-/Deicing Coatings.Biomimetics (Basel, Switzerland) · 2026Review
- Nanostructured Ti-6Al-4V Reduces Adhesion of Several Bacterial Species: An In Vitro Study.Small science · 2026Article
- Investigating Simulated Cellular Interactions on Nanostructured Surfaces with Antibacterial Properties: Insights from Force Curve Simulations.Nanomaterials (Basel, Switzerland) · 2025Article
- A supervised machine learning tool to predict the bactericidal efficiency of nanostructured surface.Journal of nanobiotechnology · 2024Article
- Platelet interaction and performance of antibacterial bioinspired nanostructures passivated with human plasma.Materials today. Bio · 2024Article
- Optimizing alkaline hydrothermal treatment for biomimetic smart metallic orthopedic and dental implants.Journal of materials science. Materials in medicine · 2024Article
- Bioactive coating provides antimicrobial protection through immunomodulation and phage therapeutics.Materials today. Bio · 2024Review
- Nanotextured titanium inhibits bacterial activity and supports cell growth on 2D and 3D substrate: A co-culture study.Biomaterials advances · 2024Article
- Damage Behavior with Atomic Force Microscopy on Anti-Bacterial Nanostructure Arrays.Nanomaterials (Basel, Switzerland) · 2024Article
- Fine-Tuning the Nanostructured Titanium Oxide Surface for Selective Biological Response.ACS applied bio materials · 2023Article
- Vancomycin tolerance of adherent Staphylococcus aureus is impeded by nanospike-induced physiological changes.NPJ biofilms and microbiomes · 2023Article
- Preferential adhesion of bacterial cells onto top- and bottom-mounted nanostructured surfaces under flow conditions.Nanoscale advances · 2023Article
- Antibacterial Applications of Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023Article
- Novel Strategy for Surface Modification of Titanium Implants towards the Improvement of Osseointegration Property and Antibiotic Local Delivery.Materials (Basel, Switzerland) · 2023Article
- Fluid Flow Induces Differential Detachment of Live and Dead Bacterial Cells from Nanostructured Surfaces.ACS omega · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Inspired by observations that the natural topography observed on cicada and dragonfly wings may be lethal to bacteria, researchers have sought to reproduce these nanostructures on biomaterials with the goal of reducing implant-associated infections. Titanium and its alloys are widely employed biomaterials with excellent properties but are susceptible to bacterial colonisation. Hydrothermal etching is a simple, cost-effective procedure which fabricates nanoscale protrusions of various dimensions upon titanium, depending on the etching parameters used. We investigated the role of etching time and the choice of cation (sodium and potassium) in the alkaline heat treatment on the topographical, physical, and bactericidal properties of the resulting modified titanium surfaces. Optimal etching times were 4 h for sodium hydroxide (NaOH) and 5 h for potassium hydroxide (KOH). NaOH etching for 4 h produced dense, but somewhat ordered, surface nanofeatures with 75 nanospikes per µm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.