Evidence map›Paper›PMID 35407183›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Novel Titanium Nanospike Structure Using Low-Energy Helium Ion Bombardment for the Transgingival Part of a Dental Implant.

Khaled Mukaddam, Monika Astasov-Frauenhoffer, Elizaveta Fasler-Kan, Laurent Marot, Marcin Kisiel, Roland Steiner, Fabien Sanchez, Ernst Meyer, Joachim Köser, Michael M Bornstein and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. HowMaterials (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Khaled MukaddamDepartment of Oral Surgery, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0001-9137-1664
Monika Astasov-FrauenhofferDepartment Research, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0001-9638-3939
Elizaveta Fasler-KanDepartment of Biomedicine, University Hospital Basel, University of Basel, Hebelstrasse 20, 4031 Basel, Switzerland.
Laurent MarotDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.ORCID 0000-0002-1529-9362
Marcin KisielDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.
Roland SteinerDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.
Fabien SanchezDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.ORCID 0000-0001-6304-2230
Ernst MeyerDepartment of Physics, University of Basel, Klingelbergstraße 82, 4056 Basel, Switzerland.ORCID 0000-0001-6385-3412
Joachim KöserInstitut für Chemie und Bioanalytik, Hochschule für Life Sciences, Hofackerstrasse 30, 4132 Muttenz, Switzerland.ORCID 0000-0002-7569-6378
Michael M BornsteinDepartment of Oral Health & Medicine, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.ORCID 0000-0002-7773-8957
Sebastian KühlDepartment of Oral Surgery, University Center for Dental Medicine Basel (UZB), University of Basel, Mattenstrasse 40, 4058 Basel, Switzerland.
University of Basel · CHUniversity of Bern · CH

Funding

Swiss Nano Institute TiSspikes
6 · The paper itself

Abstract

AIM(S): The aim of the study was to fabricate a nanospike surface on a titanium alloy surface using a newly established method of low-energy helium ion bombardment. Various methods to achieve nanospike formation on titanium have been introduced recently, and their antibacterial properties have been mainly investigated with respect to MATERIALS AND

methodsHelium sputtering was employed for developing titanium surfaces with nanospikes of 500 nm (ND) in height; commercially available smooth-machined (MD) and sandblasted and acid-etched titanium disks (SLA) were used as controls. Surface structure characterization was performed through scanning electron microscopy (SEM) and atomic force microscopy (AFM). Following incubation with

resultsSEM images confirmed the successful establishment of a nanospike surface with required heights, albeit with heterogeneity. AFM images of the 500 nm nanospike surface revealed that the roughness is dominated by large-scale hills and valleys. For frame sizes of 5 × 5 μm and smaller, the average roughness is dominated by the height of the titanium spikes. ND successfully induces dysmorphisms within CONCLUSION(S): This study successfully developed a novel titanium-nanospike-based structuration technique for titanium surfaces. In addition, the nanospikes did not hinder gingival fibroblast viability. Enhanced antimicrobial effects for such a novel nanospike-based resurfacing technique can be achieved through further optimizations for nanospike spacing and height parameters.

Indexed as

antibacterialgingival fibroblastnanospikesurfacetitanium

Identifiers

PMID35407183
PMCPMC9000873
OpenAlexW4220981388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.