ReviewFoods (Basel, Switzerland)2022
Alternatives to Cow's Milk-Based Infant Formulas in the Prevention and Management of Cow's Milk Allergy.
Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review to Reassess the Formula for Early Life Growth.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- The Preparation of Hypoallergenic Goat Milk Protein Hydrolysates via Targeted Hydrolysis of Cross-Reactive Linear Epitopes Between Cow and Goat Milk.International journal of molecular sciences · 2026Article
- Special Milk and Synthetic Biology: A Dual-Perspective Review of Ingredient Substitutions in Breast-Milk-Simulated Infant Formula.Comprehensive reviews in food science and food safety · 2026Review
- Longitudinal Evaluation from Birth to Adolescence of Soy Protein-Based Infant Formula Compared with Cow Milk-Based Formula and Breastfeeding: A Comprehensive Summary of Findings.Advances in nutrition (Bethesda, Md.) · 2026Review
- Effect of spent coffee grounds addition on the microstructure and quality characteristics of protein-fortified bread.Food chemistry: X · 2026Article
- Growth and safety of infants with cow's milk allergy receiving a new hydrolyzed rice protein-based formula containing 2-fucosyllactose and lacto-N-neotetraose: protocol for a randomized clinical trial. The RIGHT-GO study.Frontiers in nutrition · 2026Article
- The AhR-TLR4 axis in non-IgE-mediated Cow's milk allergy: a systematic review with integrated multi-omics corroboration.Frontiers in allergy · 2026Review
- Hypoallergenicity of a hydrolyzed rice protein-based formula containing 2-fucosyllactose and lacto-N-neotetraose in children with cow's milk allergy: protocol for a randomized controlled study. The RIGHT-HY study.Frontiers in nutrition · 2026Article
- Article
- Modulation of Milk Source Differences on Immunity, Nutritional Physiology and Intestinal Microbiota in Neonatal Piglets.Animals : an open access journal from MDPI · 2025Article
- Term infant formula macronutrient composition: An update for clinicians.Journal of pediatric gastroenterology and nutrition · 2025Review
- Mothers adhering to a vegan diet: feeding practices of their young children and underlying determinants - a qualitative exploration.Journal of nutritional science · 2025Article
- Species-specific N-glycan patterns in animal and human breast milk samples.Frontiers in nutrition · 2025Article
- A Comprehensive Analysis ofAnimals : an open access journal from MDPI · 2024Article
- Article
- Cow's Milk Bioactive Molecules in the Regulation of Glucose Homeostasis in Human and Animal Studies.Foods (Basel, Switzerland) · 2024Review
- Advancements in Non-Thermal Processing Technologies for Enhancing Safety and Quality of Infant and Baby Food Products: A Review.Foods (Basel, Switzerland) · 2024Review
- Quality Assessment of Reconstructed Cow, Camel and Mare Milk Powders by Near-Infrared Spectroscopy and Chemometrics.Molecules (Basel, Switzerland) · 2024Article
- Relationship between Infant Feeding and the Microbiome: Implications for Allergies and Food Intolerances.Children (Basel, Switzerland) · 2024Review
- Changes in the Fatty Acid Profile of Lactating Women Living in Poland-A Comparison with the Fatty Acid Profile of Selected Infant Formulas.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cow's milk-based infant formulas are the most common substitute to mother's milk in infancy when breastfeeding is impossible or insufficient, as cow's milk is a globally available source of mammalian proteins with high nutritional value. However, cow's milk allergy (CMA) is the most prevalent type of food allergy among infants, affecting up to 3.8% of small children. Hypoallergenic infant formulas based on hydrolysed cow's milk proteins are commercially available for the management of CMA. Yet, there is a growing demand for more options for infant feeding, both in general but especially for the prevention and management of CMA. Milk from other mammalian sources than the cow, such as goat, sheep, camel, donkey, and horse, has received some attention in the last decade due to the different protein composition profile and protein amino acid sequences, resulting in a potentially low cross-reactivity with cow's milk proteins. Recently, proteins from plant sources, such as potato, lentil, chickpeas, quinoa, in addition to soy and rice, have gained increased interest due to their climate friendly and vegan status as well as potential lower allergenicity. In this review, we provide an overview of current and potential future infant formulas and their relevance in CMA prevention and management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.