Evidence map›Paper›PMID 35406737›Full record

ArticleCells2022

A Boronated Derivative of Temozolomide Showing Enhanced Efficacy in Boron Neutron Capture Therapy of Glioblastoma.

Jing Xiang, Lin Ma, Zheng Gu, Hongjun Jin, Hongbin Zhai, Jianfei Tong, Tianjiao Liang, Juan Li, Qiushi Ren, Qi Liu

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jing XiangDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Lin MaDepartment of Stomatology, General Hospital, Shenzhen University, Shenzhen 518055, China.ORCID 0000-0002-9460-6817
Zheng GuShenzhen Bay Laboratory, Institute of Biomedical Engineering, Shenzhen 518132, China.
Hongjun JinGuangdong Provincial Key Lab of Biomedical Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China.ORCID 0000-0002-1522-1098
Hongbin ZhaiInstitute of Biomedical Engineering, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
Jianfei TongInstitute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.ORCID 0000-0003-2555-9583
Tianjiao LiangInstitute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.
Juan LiInstitute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.ORCID 0000-0003-4110-3295
Qiushi RenDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Qi LiuShenzhen Bay Laboratory, Institute of Biomedical Engineering, Shenzhen 518132, China.ORCID 0000-0002-3285-7864
Peking University · CNChinese Academy of Sciences · CNShenzhen Bay Laboratory · CNShenzhen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an incontestable need for improved treatment modality for glioblastoma due to its extraordinary resistance to traditional chemoradiation therapy. Boron neutron capture therapy (BNCT) may play a role in the future. We designed and synthesized a

Indexed as

Boron Neutron Capture TherapyBrain NeoplasmsGlioblastomaAnimalsBoron CompoundsMicePositron Emission Tomography Computed TomographyTemozolomideBoron CompoundsTemozolomidebinary radiation therapyboron delivery agentsboron neutron capture therapyglioblastoma

Identifiers

PMID35406737
PMCPMC8998031
OpenAlexW4220804901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.