Evidence map›Paper›PMID 35406677›Full record

ArticleCells2022

L-Type Ca

Julien Louradour, Olivier Bortolotti, Eleonora Torre, Isabelle Bidaud, Ned Lamb, Anne Fernandez, Jean-Yves Le Guennec, Matteo E Mangoni, Pietro Mesirca

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. L-Type CaCirculation research · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Opto-chemogenetic inhibition of L-type CaCell reports methods · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
  14. Role of CaArchives of toxicology · 2023
    Review
  15. Article
  16. Whole Exome Sequencing Identifies a Heterozygous Variant in the Cav1.3 GeneInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Rad regulation of CaNature cardiovascular research · 2022
    Article
  19. Article
  20. Paradigm shift: new concepts for HCN4 function in cardiac pacemaking.Pflugers Archiv : European journal of physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Julien LouradourInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.
Olivier BortolottiInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.ORCID 0000-0002-3669-8215
Eleonora TorreInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.
Isabelle BidaudInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.ORCID 0000-0002-1812-1447
Ned LambMammalian Stem Cell Biology Group, Institute of Human Genetics, Université de Montpellier, CNRS, 34090 Montpellier, France.
Anne FernandezMammalian Stem Cell Biology Group, Institute of Human Genetics, Université de Montpellier, CNRS, 34090 Montpellier, France.
Jean-Yves Le GuennecPhyMedExp, Université de Montpellier, INSERM U1046, UMR CNRS, 34090 Montpellier, France.
Matteo E MangoniInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.ORCID 0000-0002-8892-3373
Pietro MesircaInstitut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 34090 Montpellier, France.ORCID 0000-0002-9538-3096
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSinoatrial node cells (SANC) automaticity is generated by functional association between the activity of plasmalemmal ion channels and local diastolic intracellular Ca

methodsTo investigate the role of L-type Ca

resultsIn dormant SANC, β-adrenergic stimulation with isoproterenol (ISO) induced spontaneous action potentials (AP) and Ca

conclusionsOur study shows a novel role of Ca

Indexed as

Adrenergic AgentsSinoatrial NodeAnimalsCalciumMiceMyocytes, CardiacRyanodine Receptor Calcium Release ChannelAdrenergic AgentsCalciumRyanodine Receptor Calcium Release Channeladrenergic regulationcardiac pacemaker activityCav1.3 channelsryanodine receptors

Identifiers

PMID35406677
PMCPMC8997967
OpenAlexW4220770112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.