Evidence map›Paper›PMID 35406633›Full record

ArticleCells2022

NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer's Disease.

Idoia Blanco-Luquin, Blanca Acha, Amaya Urdánoz-Casado, Eva Gómez-Orte, Miren Roldan, Diego R Pérez-Rodríguez, Juan Cabello, Maite Mendioroz

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Boosting Neurogenesis as a Strategy in Treating Alzheimer's Disease.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Idoia Blanco-LuquinNeuroepigenetics Laboratory-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0003-2917-586X
Blanca AchaNeuroepigenetics Laboratory-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0002-6776-5644
Amaya Urdánoz-CasadoNeuroepigenetics Laboratory-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0002-6312-8330
Eva Gómez-OrteCIBIR (Center for Biomedical Research of La Rioja), 26006 Logroño, Spain.ORCID 0000-0001-6802-1746
Miren RoldanNeuroepigenetics Laboratory-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0002-7102-569X
Diego R Pérez-RodríguezNeurophysiology Department, Hospital Universitario de Navarra (HUN), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0003-4538-3466
Juan CabelloCIBIR (Center for Biomedical Research of La Rioja), 26006 Logroño, Spain.
Maite MendiorozNeuroepigenetics Laboratory-Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA (Navarra Institute for Health Research), 31008 Pamplona, Spain.ORCID 0000-0002-4179-5781
Universidad Publica de Navarra · ESCenter for Biomedical Research of La Rioja · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis

Indexed as

Alzheimer DiseaseEpigenesis, GeneticOxidoreductasesAdultHumansNeurogenesisRNA, MessengernucleoredoxinOxidoreductasesRNA, Messengeradult hippocampal neurogenesisAlzheimer’s diseaseAβ peptideCNTNAP1DNA methylationgene expressionNPCsNXNSEPT5-GP1BBTBX5

Identifiers

PMID35406633
PMCPMC8998146
OpenAlexW4221129462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.