Evidence map›Paper›PMID 35406517›Full record

ArticleCancers2022

Enhanced Recovery Pathway in Lung Resection Surgery: Program Establishment and Results of a Cohort Study Encompassing 1243 Consecutive Patients.

Yen-Lan Nguyen, Elena Maiolino, Vincent De Pauw, Mathilde Prieto, Antonio Mazzella, Jean-Baptiste Peretout, Agnès Dechartres, Christophe Baillard, Antonio Bobbio, Elisa Daffré and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Establishment of Thoracic Surgical Difficulty Assessment Scale based on Delphi method.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yen-Lan NguyenAnesthesiology and Critical Care Medicine Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Elena MaiolinoThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Vincent De PauwThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Mathilde PrietoThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Antonio MazzellaThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.ORCID 0000-0002-5330-5495
Jean-Baptiste PeretoutAnesthesiology and Critical Care Medicine Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Agnès DechartresDépartement Biostatistique Santé Publique et Information Médicale, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, AP-HP, 75013 Paris, France.
Christophe BaillardAnesthesiology and Critical Care Medicine Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Antonio BobbioThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Elisa DaffréThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.
Marco AlifanoThoracic Surgical Department, Cochin Academic Hospital, APHP, Université de Paris, 75014 Paris, France.ORCID 0000-0002-2038-1037
Université Paris Cité · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn spite of increasing diffusion, Enhanced Recovery Pathways (ERP) have been scarcely assessed in large scale programs of lung cancer surgery. The aim of this study was auditing our practice.

methodsA two-step audit program was established: the first dealing with our initial ERP experience in patients undergoing non-extended anatomical segmentectomies and lobectomies, the second including all consecutive patients undergoing all kind of lung resections for NSCLC. The first step aimed at auditing results of ERP on occurrence of postoperative complications and at assessing which ERP components are associated with improved short-term outcomes. We also audited late results by assessing long-term survival of patients in the first step of our study. The second step aimed at auditing on large-scale short-term results of the ERP in a real-life setting.

resultsOver a one-year period, 166 patients were included. The median number of ERP procedures per patient was three (IQR 3-4). No postoperative death occurred. The overall adverse events rate was 30%. In multivariate analyzes, the only element associated with reduced adverse postoperative events was chest tube withdrawal within POD2 (OR = 0.21, 95% CI (0.10-0.46)). The 1-, 3-, and 5-year survival rates were 97%, 86.1%, and 76.3%, respectively. In the second period, 1077 patients were included in our ERP; 11 patients died during the postoperative period or within 30 days of operation (1.02%). The overall postoperative adverse event rate was 30.3%, major complication occurring in 134 (12.4%), and minor ones in 192 (17.8%). Respiratory complications occurred in 64 (5.9%). Thoracoscore independently predicted postoperative death, the occurrence of complications (all-kind, minor, major, or respiratory ones).

conclusionsCompliance to ERP procedures and early chest tube removal are associated with reduced postoperative events in patients with lung resection surgery. In a large setting scale, ERP can be applied with satisfactory results in terms of mortality and morbidity. Thoracoscore is a useful tool in predicting mortality and postoperative adverse events.

Indexed as

chest tube managementenhanced recovery pathwaylung surgery

Identifiers

PMID35406517
PMCPMC8997103
OpenAlexW4220714357

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.