Evidence map›Paper›PMID 35406429›Full record

ReviewCancers2022

Radiomics/Radiogenomics in Lung Cancer: Basic Principles and Initial Clinical Results.

Athanasios K Anagnostopoulos, Anastasios Gaitanis, Ioannis Gkiozos, Emmanouil I Athanasiadis, Sofia N Chatziioannou, Konstantinos N Syrigos, Dimitris Thanos, Achilles N Chatziioannou, Nikolaos Papanikolaou

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Mechanisms of primary resistance to immune checkpoint inhibitors in NSCLC.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Radiomics analysis in medical imaging research.Journal of medical radiation sciences · 2023
    Article
  15. Review
  16. Imaging in translational cancer research.Cancer biology & medicine · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Athanasios K AnagnostopoulosDivision of Biotechnology, Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11525 Athens, Greece.ORCID 0000-0001-5161-7850
Anastasios GaitanisClinical and Translational Research, Center of Experimental Surgery, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.
Ioannis GkiozosThird Department of Internal Medicine, "Sotiria" Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-2902-3391
Emmanouil I AthanasiadisGreek Genome Centre, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.ORCID 0000-0002-2771-5562
Sofia N ChatziioannouNuclear Medicine Division, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.ORCID 0000-0002-8344-8219
Konstantinos N SyrigosThird Department of Internal Medicine, "Sotiria" Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Dimitris ThanosGreek Genome Centre, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.
Achilles N ChatziioannouFirst Department of Radiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Nikolaos PapanikolaouComputational Clinical Imaging Group, Centre for the Unknown, Champalimaud Foundation, 1400-038 Lisbon, Portugal.ORCID 0000-0003-3298-2072
Biomedical Research Foundation of the Academy of Athens · GRNational and Kapodistrian University of Athens · GRChampalimaud Foundation · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide, and elucidation of its complicated pathobiology has been traditionally targeted by studies incorporating genomic as well other high-throughput approaches. Recently, a collection of methods used for cancer imaging, supplemented by quantitative aspects leading towards imaging biomarker assessment termed "radiomics", has introduced a novel dimension in cancer research. Integration of genomics and radiomics approaches, where identifying the biological basis of imaging phenotypes is feasible due to the establishment of associations between molecular features at the genomic-transcriptomic-proteomic level and radiological features, has recently emerged termed radiogenomics. This review article aims to briefly describe the main aspects of radiogenomics, while discussing its basic limitations related to lung cancer clinical applications for clinicians, researchers and patients.

Indexed as

image sciencelearning algorithmslung cancerradiogenomicsradiomicsreview

Identifiers

PMID35406429
PMCPMC8997041
OpenAlexW4220956987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.