Evidence map›Paper›PMID 35406416›Full record

ArticleCancers2022

Prediction of Incontinence after Robot-Assisted Radical Prostatectomy: Development and Validation of a 24-Month Incontinence Nomogram.

Ruben M Pinkhasov, Timothy Lee, Rogerio Huang, Bonnie Berkley, Alexandr M Pinkhasov, Nicole Dodge, Matthew S Loecher, Gaybrielle James, Elena Pop, Kristopher Attwood and 1 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  7. [First cohort: Robotic radical prostatectomy at the Mexican Institute for Social Security].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruben M PinkhasovDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0001-9160-7841
Timothy LeeDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Rogerio HuangDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Bonnie BerkleyDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Alexandr M PinkhasovDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Nicole DodgeDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Matthew S LoecherDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Gaybrielle JamesDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Elena PopDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Kristopher AttwoodDepartment of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
James L MohlerDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.ORCID 0000-0002-7726-3795

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
NCI NIH HHS P30CA016056Roswell Park Cancer Institute Friends of Urology
6 · The paper itself

Abstract

Incontinence after robot-assisted radical prostatectomy (RARP) is feared by most patients with prostate cancer. Many risk factors for incontinence after RARP are known, but a paucity of data integrates them. Prospectively acquired data from 680 men who underwent RARP January 2008-December 2015 and met inclusion/exclusion criteria were queried retrospectively and then divided into model development (80%) and validation (20%) cohorts. The UCLA-PCI-Short Form-v2 Urinary Function questionnaire was used to categorize perfect continence (0 pads), social continence (1-2 pads), or incontinence (≥3 pads). The observed incontinence rates were 26% at 6 months, 7% at 12 months, and 3% at 24 months. Logistic regression was used for model development, with variables identified using a backward selection process. Variables found predictive included age, race, body mass index, and preoperative erectile function. Internal validation and calibration were performed using standard bootstrap methodology. Calibration plots and receiver operating curves were used to evaluate model performance. The initial model had 6-, 12-, and 24-month areas under the curves (AUCs) of 0.64, 0.66, and 0.80, respectively. The recalibrated model had 6-, 12-, and 24-month AUCs of 0.52, 0.52, and 0.76, respectively. The final model was superior to any single clinical variable for predicting the risk of incontinence after RARP.

Indexed as

nomogramrobot-assisted radical prostatectomyurinary incontinence

Identifiers

PMID35406416
PMCPMC8997126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.