Evidence map›Paper›PMID 35406402›Full record

ArticleCancers2022

Biopsy Ratio of Suspected to Confirmed Sarcoma Diagnosis.

Nasian Mosku, Philip Heesen, Gabriela Studer, Beata Bode, Vito Spataro, Natalie D Klass, Lars Kern, Mario F Scaglioni, Bruno Fuchs

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Telomeres and telomerase in Sarcoma disease and therapy.International journal of medical sciences · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nasian MoskuFaculty of Medicine, University of Lucerne, 6000 Lucerne, Switzerland.ORCID 0000-0002-4530-7554
Philip HeesenSwiss Sarcoma Network, 6000 Lucerne, Switzerland.ORCID 0000-0002-5090-4935
Gabriela StuderFaculty of Medicine, University of Lucerne, 6000 Lucerne, Switzerland.
Beata BodeSwiss Sarcoma Network, 6000 Lucerne, Switzerland.
Vito SpataroSwiss Sarcoma Network, 6000 Lucerne, Switzerland.
Natalie D KlassSwiss Sarcoma Network, 6000 Lucerne, Switzerland.ORCID 0000-0003-3582-9508
Lars KernSwiss Sarcoma Network, 6000 Lucerne, Switzerland.
Mario F ScaglioniFaculty of Medicine, University of Lucerne, 6000 Lucerne, Switzerland.ORCID 0000-0001-5289-9140
Bruno FuchsFaculty of Medicine, University of Lucerne, 6000 Lucerne, Switzerland.
Swisscom (Switzerland) · CHUniversity of Lucerne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ratio of malignancy in suspicious soft tissue and bone neoplasms (RMST) has not been often addressed in the literature. However, this value is important to understand whether biopsies are performed too often, or not often enough, and may therefore serve as a quality indicator of work-up for a multidisciplinary team (MDT). A prerequisite for the RMST of an MDT is the assessment of absolute real-world data to avoid bias and to allow comparison among other MDTs. Analyzing 950 consecutive biopsies for sarcoma-suspected lesions over a 3.2-year period, 55% sarcomas were confirmed; 28% turned out to be benign mesenchymal tumors, and 17% non-mesenchymal tumors, respectively. Of these, 3.5% were metastases from other solid malignancies, 1.5% hematologic tumors and 13% sarcoma simulators, which most often were degenerative or inflammatory processes. The RMST for biopsied lipomatous lesions was 39%. The ratio of unplanned resections was 10% in this series. Reorganizing sarcoma work-up into integrating practice units (IPU) allows the assessment of real-world data with absolute values over the geography, thereby enabling the definition of quality indicators and addressing cost efficiency aspects of sarcoma care.

Indexed as

biopsyconfirmationratiosarcomasuspicion

Identifiers

PMID35406402
PMCPMC8996854
OpenAlexW4223421475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.