Evidence map›Paper›PMID 35406397›Full record

ArticleCancers2022

Regulation of Let-7a-5p and miR-199a-5p Expression by Akt1 Modulates Prostate Cancer Epithelial-to-Mesenchymal Transition via the Transforming Growth Factor-β Pathway.

Abdulrahman Alwhaibi, Varun Parvathagiri, Arti Verma, Sandeep Artham, Mir S Adil, Payaningal R Somanath

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Abdulrahman AlwhaibiClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.ORCID 0000-0001-8519-3363
Varun ParvathagiriClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.
Arti VermaClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.
Sandeep ArthamClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.ORCID 0000-0002-0556-8979
Mir S AdilClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.ORCID 0000-0002-2129-1228
Payaningal R SomanathClinical and Experimental Therapeutics, University of Georgia, Augusta, GA 30912, USA.ORCID 0000-0003-3017-0230
University of Georgia · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1TR002378
6 · The paper itself

Abstract

Akt1 suppression in advanced cancers has been indicated to promote metastasis. Our understanding of how Akt1 orchestrates this is incomplete. Using the NanoString

Indexed as

Akt1epithelial-to-mesenchymal transitionlet-7a-5pmiR-199a-5pprostate cancer

Identifiers

PMID35406397
PMCPMC8996869
OpenAlexW4220983950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.