Evidence map›Paper›PMID 35406250›Full record

ArticlePolymers2022

3D Printed Strontium and Zinc Doped Hydroxyapatite Loaded PEEK for Craniomaxillofacial Implants.

Faisal Manzoor, Atefeh Golbang, Dorian Dixon, Elena Mancuso, Usaid Azhar, Ioannis Manolakis, Daniel Crawford, Alistair McIlhagger, Eileen Harkin-Jones

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Latest Research of Doped Hydroxyapatite for Bone Tissue Engineering.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Faisal ManzoorDepartment of Mechanical Engineering, School of Engineering, Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.
Atefeh GolbangDepartment of Mechanical Engineering, School of Engineering, Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.ORCID 0000-0002-2454-0154
Dorian DixonNanotechnology and Integrated Bio-Engineering Centre (NIBEC), Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.
Elena MancusoNanotechnology and Integrated Bio-Engineering Centre (NIBEC), Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.ORCID 0000-0003-1742-1656
Usaid AzharPrecision Engineering, Materials & Manufacturing (PEM) Research Centre, Institute of Technology Sligo, Ash Lane, F91 YW50 Sligo, Ireland.
Ioannis ManolakisPrecision Engineering, Materials & Manufacturing (PEM) Research Centre, Institute of Technology Sligo, Ash Lane, F91 YW50 Sligo, Ireland.ORCID 0000-0003-4252-3849
Daniel CrawfordAxial 3D, Alexander House, 17a Ormeau Ave, Belfast BT2 8HD, UK.
Alistair McIlhaggerDepartment of Mechanical Engineering, School of Engineering, Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.
Eileen Harkin-JonesDepartment of Mechanical Engineering, School of Engineering, Ulster University, Shore Road, Newtownabbey BT37 0QB, UK.

Funding

EU's INTERREG VA Programmes managed by SEUPB IVA5055
6 · The paper itself

Abstract

In this study, Strontium (Sr) and Zinc (Zn) doped-HA nanoparticles were synthesized and incorporated into polyetheretherketone (PEEK) up to 30 wt.% and processed by a novel approach i.e., fused deposition modelling (FDM) 3D printing for the production of patient specific cranial implants with improved bioactivity and the required mechanical performance. Filaments were produced via extrusion and subsequently 3D-printed using FDM. To further improve the bioactivity of the 3D-printed parts, the samples were dip-coated in polyethylene glycol-DOPA (PEG-DOPA) solution. The printing quality was influenced by filler loading, but was not significantly influenced by the nature of doped-HA. Hence, the printing conditions were optimized for each sample. Micro-CT and Scanning Electron Microscopy (SEM) showed a uniform distribution of bioceramic particles in PEEK. Although agglomeration of particles increased with increase in filler loadings. Differential Scanning Calorimetry (DSC) showed that the melting point and crystallinity of PEEK increased with an increase in doped-HA loading from 343 °C to 355 °C and 27.7% to 34.6%, respectively. Apatite formation was confirmed on the 3D-printed samples after immersion in simulated body fluid (SBF) for 7, 14 and 28 days via SEM, X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR). The tensile strength and impact strength decreased from 75 MPa to 51 MPa and 14 kJ/m

Indexed as

3D printingbioactive compositesdoped hydroxyapatitefused deposition modellingPEEK

Identifiers

PMID35406250
PMCPMC9002955

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.