Evidence map›Paper›PMID 35406141›Full record

ReviewNutrients2022

CRABP1 in Non-Canonical Activities of Retinoic Acid in Health and Diseases.

Jennifer Nhieu, Yu-Lung Lin, Li-Na Wei

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Retinoic acid in health and disease.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Article
  4. Monogenic Contributions to Familial Endometriosis: A Scoping Review.Gynecologic and obstetric investigation · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. CRABP1-complexes in exosome secretion.Cell communication and signaling : CCS · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer NhieuDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Yu-Lung LinDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-5437-9958
Li-Na WeiDepartment of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-6376-8506
University of Minnesota · US

Funding

Characterization of KIFAP3, a Modifier of Survival in Sporadic ALSR01NS065847 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LANDERS, JOHN E · 2010 to 2014
$1.8M
Non-canonical signaling of retinoic acid by Cellular Retinoic Acid Binding Protein 1F31DK123999 · NIDDK · UNIVERSITY OF MINNESOTA · PI NHIEU, JENNIFER · 2020 to 2023
$141k
National Institute of Health DK54733National Institute of Health DK60521NIDDK NIH HHS F31 DK123999NINDS NIH HHS R01 NS065847
6 · The paper itself

Abstract

In this review, we discuss the emerging role of Cellular Retinoic Acid Binding Protein 1 (CRABP1) as a mediator of non-canonical activities of retinoic acid (RA) and relevance to human diseases. We first discuss the role of CRABP1 in regulating MAPK activities and its implication in stem cell proliferation, cancers, adipocyte health, and neuro-immune regulation. We then discuss an additional role of CRABP1 in regulating CaMKII activities, and its implication in heart and motor neuron diseases. Through molecular and genetic studies of

Indexed as

Receptors, Retinoic AcidTretinoinAnimalsHeartHumansMiceMice, KnockoutSignal TransductionReceptors, Retinoic AcidTretinoinCAMKIIcancerCRABP1human diseaseinflammationMAPKmetabolismneurodegenerationnon-canonicalretinoic acid

Identifiers

PMID35406141
PMCPMC9003107
OpenAlexW4223634323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.