Evidence map›Paper›PMID 35406107›Full record

ReviewNutrients2022

Cytokinins: Wide-Spread Signaling Hormones from Plants to Humans with High Medical Potential.

Moustafa Fathy, Sahar M Saad Eldin, Muhammad Naseem, Thomas Dandekar, Eman M Othman

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Epistatic interaction of the genesbioRxiv : the preprint server for biology · 2026
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  3. Article
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  6. Article
  7. Article
  8. Article
  9. New NDoklady. Biochemistry and biophysics · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. On the human health benefits of microalgal phytohormones: An explorativeComputational and structural biotechnology journal · 2023
    Article
  16. Article
  17. Article
  18. A New EGFR Inhibitor fromCurrent issues in molecular biology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Moustafa FathyDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-0734-5007
Sahar M Saad EldinDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Muhammad NaseemDepartment of Life and Environmental Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates.
Thomas DandekarDepartment of Bioinformatics, Biocenter, University of Wuerzburg, Am Hubland, 97074 Wuerzburg, Germany.ORCID 0000-0003-1886-7625
Eman M OthmanDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
University of Würzburg · DEMinia University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nature is a rich source of biologically active novel compounds. Sixty years ago, the plant hormones cytokinins were first discovered. These play a major role in cell division and cell differentiation. They affect organogenesis in plant tissue cultures and contribute to many other physiological and developmental processes in plants. Consequently, the effect of cytokinins on mammalian cells has caught the attention of researchers. Many reports on the contribution and potential of cytokinins in the therapy of different human diseases and pathophysiological conditions have been published and are reviewed here. We compare cytokinin effects and pathways in plants and mammalian systems and highlight the most important biological activities. We present the strong profile of the biological actions of cytokinins and their possible therapeutic applications.

Indexed as

CytokininsPlantsAnimalsHormonesHumansMammalsPlant Growth RegulatorsSignal TransductionCytokininsHormonesPlant Growth Regulatorsbiological activitiescytokininsmammalian systemphytohormonesplant system

Identifiers

PMID35406107
PMCPMC9003334
OpenAlexW4223474350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.