Evidence map›Paper›PMID 35406105›Full record

ReviewNutrients2022

A Molecular Approach to Understanding the Role of Diet in Cancer-Related Fatigue: Challenges and Future Opportunities.

Sylvia L Crowder, Mary C Playdon, Lisa M Gudenkauf, Jennifer Ose, Biljana Gigic, Leigh Greathouse, Anita R Peoples, Alix G Sleight, Heather S L Jim, Jane C Figueiredo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02328677 (ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02328677 recruitingnot on this map

ColoCare Transdisciplinary Research in Colorectal Cancer Prognosis

TypeobservationalSponsorUniversity of UtahRan2007 to 2030Enrolled5,000ConditionsColorectal Cancer
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Cancer-related fatigue in cancer survivors: an updated clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Sylvia L CrowderDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33617, USA.ORCID 0000-0003-1430-9810
Mary C PlaydonCancer Control and Population Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-6082-0447
Lisa M GudenkaufDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33617, USA.
Jennifer OseDepartment of Population Health Sciences, University of Utah, Salt Lake City, UT 84112, USA.
Biljana GigicDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69047 Heidelberg, Germany.ORCID 0000-0002-8085-2072
Leigh GreathouseHuman Science and Design, Robbins College of Health and Human Sciences, Baylor University, Waco, TX 76798, USA.ORCID 0000-0002-6855-8516
Anita R PeoplesDepartment of Population Health Sciences, University of Utah, Salt Lake City, UT 84112, USA.
Alix G SleightDepartment of Physical Medicine and Rehabilitation, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-5317-060X
Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33617, USA.ORCID 0000-0001-7353-3711
Jane C FigueiredoCenter for Integrated Research in Cancer and Lifestyle, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Moffitt Cancer Center · USUniversity of Utah · USCedars-Sinai Medical Center · USBaylor University · USHeidelberg University · DE

Funding

Transdisciplinary Team Science in Colorectal Cancer Prognosis: the ColoCare StudyU01CA206110 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jane C. Figueiredo, Christopher I Li · 2016 to 2026
$18.6M
Behavioral Oncology Education & Career DevelopmentT32CA090314 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Vani N Simmons, SUSAN T VADAPARAMPIL · 2019 to 2026
$2.9M
NCI NIH HHS NR018762NCI NIH HHS T32 CA090314NCI NIH HHS T32CA090314NCI NIH HHS U01 CA206110
6 · The paper itself

Abstract

Cancer-related fatigue (CRF) is considered one of the most frequent and distressing symptoms for cancer survivors. Despite its high prevalence, factors that predispose, precipitate, and perpetuate CRF are poorly understood. Emerging research focuses on cancer and treatment-related nutritional complications, changes in body composition, and nutritional deficiencies that can compound CRF. Nutritional metabolomics, the novel study of diet-related metabolites in cells, tissues, and biofluids, offers a promising tool to further address these research gaps. In this position paper, we examine CRF risk factors, summarize metabolomics studies of CRF, outline dietary recommendations for the prevention and management of CRF in cancer survivorship, and identify knowledge gaps and challenges in applying nutritional metabolomics to understand dietary contributions to CRF over the cancer survivorship trajectory.

Indexed as

Cancer SurvivorsNeoplasmsDietFatigueHumansPrevalencecancer survivorsdietary interventiondiet-related diseasemetabolomicsnutrition

Identifiers

PMID35406105
PMCPMC9003400
OpenAlexW4223612769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.