ArticleNutrients2022
Association between Serum Vitamin A, Blood Lipid Level and Dyslipidemia among Chinese Children and Adolescents.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Cystine: A Key Protective Factor Against Childhood Hypo-HDL Cholesterolemia and Dyslipidemia-A Matched Case-Control Study.Nutrients · 2026Observational
- Vitamin Status and Risk of Age-Related Diseases Among Adult Residents of the Pearl River Delta Region.Nutrients · 2025Article
- Impact of serum lipid on recurrence of uterine fibroids: a single center retrospective study.BMC women's health · 2024Article
- Correction of plasma fat-soluble vitamin levels by blood lipids in elderly patients with coronary heart disease.Practical laboratory medicine · 2024Article
- Cardiovascular Risk Factors in China.Journal of geriatric cardiology : JGC · 2024Article
- Assessment of serum Vit A, D and zinc nutritional status and related dietary and exercise behaviors of children and adolescents in rural and urban area.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
15 authors at 8 institutions in 1 country.
Funding
Abstract
Background: To study the relationship between serum vitamin A (VA) level and blood lipid profiles in children and adolescents aged 6−18 years, as well as the effect of VA on dyslipidemia. Methods: The project adopted a multistage stratified cluster sampling method. The Food Frequency Questionnaire (FFQ) was used to obtain dietary factors data. Blood samples of subjects were taken via venipuncture. Generalized linear models were used to explore the correlation be-tween VA and biochemical indicators, as well as stratified and inter-actions analysis to explore the influence of confounders on these relationships. Generalized linear models were constructed to explore the association between VA and blood lipids. Restricted cubic splines were used to characterize dose−response associations between serum VA and dyslipidemia based on logistic regression. Results: Serum VA was positively correlated with TC, TG and HDL-C (p < 0.05), but these associations were influenced by age (p < 0.05). The adjusted odds ratio (OR) values of VA for hypercho lesterolemia, hypertriglyceridemia, mixed hyperlipidemia and low high-density lipoprotein cholesterolemia were 3.283, 3.239, 5.219 and 0.346, respectively (p < 0.01). Meanwhile, significant age interactions affected the relationship between VA and TC, as well as TG and LDL-C (p < 0.01). Conclusion: Serum VA was positively correlated with blood lipids, but these associations were influenced by age. VA was a risk factor for dyslipidemias, such as hypercholesterolemia, hypertriglyceridemia and mixed hyperlipidemia, but was a protective factor for low high-density lipoprotein cholesterolemia.
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Registered trials
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