Evidence map›Paper›PMID 35406030›Full record

ArticleNutrients2022

The Neuroprotection of Verbascoside in Alzheimer's Disease Mediated through Mitigation of Neuroinflammation via Blocking NF-κB-p65 Signaling.

Shanshan Chen, Honghan Liu, Shimiao Wang, Hongbo Jiang, Le Gao, Lu Wang, Lesheng Teng, Chunyue Wang, Di Wang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  7. Article
  8. Review
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  14. Review
  15. Article
  16. Article
  17. IL-1β and CXCR4 as Potential Therapeutic Targets for Alzheimer's Disease.Combinatorial chemistry & high throughput screening · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shanshan ChenSchool of Life Sciences, Jilin University, Changchun 130012, China.
Honghan LiuSchool of Life Sciences, Jilin University, Changchun 130012, China.
Shimiao WangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Hongbo JiangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Le GaoSchool of Life Sciences, Jilin University, Changchun 130012, China.
Lu WangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Lesheng TengSchool of Life Sciences, Jilin University, Changchun 130012, China.ORCID 0000-0003-1623-5384
Chunyue WangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Di WangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Jilin University · CN

Funding

the Jilin Province Science and Technology Development Plan (Medicine and Health Spe-cial Project) 20191102027YYthe Jilin Province Science and Technology Development Plan (Medicine and Health Spe-cial Project) 20200708037YYthe Jilin Province Science and Technology Development Plan (Medicine and Health Spe-cial Project) 20200708068YY
6 · The paper itself

Abstract

Verbascoside (VB) is a phenylethanoid glycoside extracted from the herbaceous plant

Indexed as

Alzheimer DiseaseGlucosidesNeuroprotective AgentsPhenolsTranscription Factor RelAAnimalsLipopolysaccharidesMiceMicrogliaNeuroinflammatory DiseasesNeuroprotectionNF-kappa BPolyphenolsProteomicsacteosideGlucosidesLipopolysaccharidesNeuroprotective AgentsNF-kappa BPhenolsPolyphenolsRela protein, mouseTranscription Factor RelAAlzheimer’s diseaseneuroinflammationneuroprotectionNF-κB signalingverbascoside

Identifiers

PMID35406030
PMCPMC9003273
OpenAlexW4220969099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.