Evidence map›Paper›PMID 35405978›Full record

ArticleNutrients2022

Plasma Retinoid Concentrations Are Altered in Pregnant Women.

Lindsay C Czuba, Emily E Fay, Jeffrey LaFrance, Chase K Smith, Sara Shum, Sue L Moreni, Jennie Mao, Nina Isoherranen, Mary F Hebert

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03117660 (Effects of Retinoids on CYP2D6 Activity and Variability in Special Populations), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03117660 phase1completednot on this map

Effects of Retinoids on CYP2D6 Activity and Variability in Special Populations

TypeinterventionalSponsorUniversity of WashingtonRan2017 to 2022Enrolled82ConditionsCYP2D6 PolymorphismArmsVitamin A
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Sex and Age but Not Body Mass Index (BMI) Predict Serum Retinol Binding Protein 4 (RBP4) and Transthyretin (TTR) Concentrations.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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  7. Article
  8. Review
  9. Article
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  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lindsay C CzubaDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-9142-5706
Emily E FayDepartment of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Jeffrey LaFranceDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
Chase K SmithDepartment of Pharmacy, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
Sara ShumDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
Sue L MoreniDepartment of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Jennie MaoDepartment of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Nina IsoherranenDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-9548-3126
Mary F HebertDepartment of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
University of Washington · US

Funding

Diabetes, Obesity and Metabolism Training ProgramT32DK007247 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON, KRISTINA Marie UTZSCHNEIDER · 1986 to 2026
$10.0M
NRSA Training CoreTL1TR002318 · NCATS · UNIVERSITY OF WASHINGTON · PI Megan Moore · 2017 to 2026
$8.4M
Effects of Retinoids on CYP2D6 Activity and Variability in Special PopulationsR01GM124264 · NIGMS · UNIVERSITY OF WASHINGTON · PI HEBERT, MARY F · 2017 to 2020
$2.3M
NCATS NIH HHS TL1 TR002318NIDDK NIH HHS T32 DK007247NIGMS NIH HHS R01GM124264
6 · The paper itself

Abstract

Vitamin A is vital to maternal-fetal health and pregnancy outcomes. However, little is known about pregnancy associated changes in maternal vitamin A homeostasis and concentrations of circulating retinol metabolites. The goal of this study was to characterize retinoid concentrations in healthy women (

Indexed as

PrealbuminVitamin AFemaleHumansPregnancyPregnant PeopleRetinoidsRetinol-Binding Proteins, PlasmaTretinoinPrealbuminRBP4 protein, humanRetinoidsRetinol-Binding Proteins, PlasmaTretinoinVitamin Apostpartumpregnancyretinoidretinol-binding protein 4 (RBP4)transthyretin (TTR)vitamin A

Identifiers

PMID35405978
PMCPMC9002937
OpenAlexW4221108728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.