Evidence map›Paper›PMID 35405962›Full record

ArticleNutrients2022

Antioxidant and Anti-Inflammatory Properties of Rubber Seed Oil in Lipopolysaccharide-Induced RAW 267.4 Macrophages.

Jing Liu, Lulu Zhao, Hongying Cai, Zitao Zhao, Yongbao Wu, Zhiguo Wen, Peilong Yang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Standardized aqueous extract ofFrontiers in pharmacology · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jing LiuInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0003-0439-9066
Lulu ZhaoInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Hongying CaiInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Zitao ZhaoInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0003-0598-1058
Yongbao WuInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Zhiguo WenInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Peilong YangInstitute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Chinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rubber seed oil (RSO) is a typical PUFA-enriched plant oil, but it has not been widely used as a healthy edible oil resource due to the lack of understanding of its nutritional values, health biological effects, and action mechanisms. This work was conducted to characterize the basic physicochemical properties, evaluate the antioxidant and anti-inflammatory properties, and explore the involved mechanisms of RSO in LPS-induced RAW 264.7 cells. In the present study, the basic physicochemical parameters of RSO indicated that RSO has good qualities as a potential edible plant oil resource. In LPS-induced macrophages, RSO supplementation displayed a significant antioxidant effect by decreasing ROS and MDA levels as well as elevating T-AOC. In addition, RSO supplementation showed an anti-inflammatory effect by reducing the production of NO, IL-1

Indexed as

AntioxidantsLipopolysaccharidesAnimalsAnti-Inflammatory AgentsFats, UnsaturatedInflammationInterleukin-10Interleukin-6MacrophagesMiceNF-kappa BRAW 264.7 CellsRNA, MessengerTumor Necrosis Factor-alphaAnti-Inflammatory AgentsAntioxidantsFats, UnsaturatedInterleukin-10Interleukin-6LipopolysaccharidesNF-kappa BRNA, Messengerrubber seed oilTumor Necrosis Factor-alphaanti-inflammatoryantioxidantNF-κB signal pathwayNrf2 signal pathwayrubber seed oil

Identifiers

PMID35405962
PMCPMC9003255
OpenAlexW4221125646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.