ArticleNutrients2022
Baseline Objective Malnutritional Indices as Immune-Nutritional Predictors of Long-Term Recurrence in Patients with Acute Ischemic Stroke.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Association of preoperative prognostic nutritional index with risk of postoperative delirium: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Albumin-based nutritional-inflammatory indices and prognosis in critically ill patients with acute myocardial infarction: a MIMIC-IV cohort study.BMC cardiovascular disorders · 2026Article
- Predictive value of preoperative and postoperative controlling nutritional status scores and their changes in older patients with large vessel occlusion stroke after endovascular thrombectomy.Frontiers in nutrition · 2026Article
- Impact of coexisting obesity and malnutrition on the clinical outcomes of acute ischemic stroke patients treated with intravenous thrombolysis: a cohort-based study.Frontiers in nutrition · 2026Article
- Association between PNI and all-cause mortality in ischemic stroke patients: a large-scale retrospective cohort study.Frontiers in nutrition · 2026Article
- Development and validation of a novel nutrition-inflammation prognostic score for predicting 30-day mortality in critically ill stroke patients.Frontiers in nutrition · 2025Article
- Objective nutritional indices as an independent predictor of functional outcome after endovascular therapy for acute ischemic stroke: a cohort study in a Chinese population.Frontiers in nutrition · 2025Article
- Association between serum A/G ratio and stroke: data from NHANES 2009-2020.Frontiers in nutrition · 2025Article
- The prognostic significance of malnutrition in older adult patients with acute ischemic stroke.Frontiers in nutrition · 2025Article
- A nomogram model for predicting postoperative prognosis in patients with aneurysmal subarachnoid hemorrhage using preoperative biochemical indices.BMC neurology · 2024Article
- Predictive value of the random forest model based on bioelectrical impedance analysis parameter trajectories for short-term prognosis in stroke patients.European journal of medical research · 2024Article
- A one-year relapse prediction model for acute ischemic stroke (AIS) based on clinical big data.Heliyon · 2024Article
- Effect of nutritional status on occurrence of pneumonia after traumatic cervical spinal cord injury.Scientific reports · 2024Article
- Article
- Geriatric nutrition risk index: a more powerful index identifying muscle mass loss in patients with rheumatoid arthritis.Clinical rheumatology · 2024Article
- Association of malnutrition status with 30-day mortality in patients with sepsis using objective nutritional indices: a multicenter retrospective study in South Korea.Acute and critical care · 2024Article
- Association Apo B/Apo a-1 Ratio and Prognostic Nutritional Index with 90-Day Outcomes of Acute Ischemic Stroke.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- The Role of Nutrition in Neurological Disorders.Nutrients · 2023Article
- Predictive value of Prognostic Nutritional Index (PNI) for the severity of vasculogenic erectile dysfunction.International urology and nephrology · 2023Article
- Association between Malnutrition and Migraine Risk Assessed Using Objective Nutritional Indices.Nutrients · 2023Article
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12 authors at 2 institutions in 1 country.
Funding
Abstract
Background: The controlling nutritional status (CONUT) score and the prognostic nutritional index (PNI) score were designed as indicators of patients’ immune-nutritional status. This study aimed to investigate the prognostic impact of the CONUT and PNI scores on long-term recurrent ischemic stroke (RIS) and adverse outcomes for adults with acute ischemic stroke (AIS). Methods: This retrospective study enrolled 991 AIS patients. Multivariable Cox regression models were used to assess the relationships of the malnutritional indices and RIS and major cardiovascular events (MACEs). Results: During a median follow-up at 44 months (IQR 39−49 months), 203 (19.2%) patients had RIS and 261 (26.3%) had MACEs. Compared with normal nutritional status, moderate to severe malnutrition was significantly related to an increased risk of RIS in the CONUT score (adjusted hazard ratio (HR) 3.472, 95% confidence interval (CI) 2.223−5.432, p < 0.001). A higher PNI value tertile (tertile two, adjusted HR 0.295, 95% CI 0.202−0.430; tertile three, adjusted HR 0.445, 95% CI 0.308−0.632, all p < 0.001) was related to a lower risk of RIS. Similar results were found for MACEs. The PNI exhibited nonlinear association with the RIS and both two malnutritional indices improved the model’s discrimination when added to the model with other clinical risk factors. Conclusions: This study demonstrated that the CONUT and PNI are promising, straightforward screening indicators to identify AIS patients with impaired immune-nutritional status at higher risk of long-term RIS and MACEs.
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