ArticleAMA journal of ethics2022
How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?
Article in AMA journal of ethics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex, Racial, and Ethnic Representation in COVID-19 Clinical Trials: A Systematic Review and Meta-analysis.JAMA internal medicine · 2023Pooled it
- Recruitment and Retention of Racially Minoritized Families in a Pediatric Behavioral Diabetes Research Study.Journal of clinical psychology in medical settings · 2026Article
- Beyond Words: A Call to Action for Language Inclusivity in Prospective Research.Journal of general internal medicine · 2026Article
- Lessons from the field: culturally grounded approaches to recruiting Chinese American immigrant cancer patients to psycho-oncology trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Language Barriers Limit Clinical Trial Accessibility for Patients With Gastrointestinal Cancer.Gastroenterology · 2026Article
- Virtual delivery of evidence-based, person-centered breastfeeding peer counseling: a qualitative evaluation of women's experiences and perceptions.International breastfeeding journal · 2026Article
- Liquid biopsies using circulating tumor DNA for surveillance of gastrointestinal cancers in Hispanics: first real-world data report.ESMO real world data and digital oncology · 2026Article
- Cancer care disparities among patients with limited English proficiency: challenges and strategies for equity.BJC reports · 2025Review
- Observational
- Establishing best practices guidelines for collaborative research in global surgery: developing a Delphi survey.Journal of global health · 2025Article
- Time to Listen: Engaging Latino Autistic Adults and Parents as Partners in Advancing Autism Research.Journal of autism and developmental disorders · 2025Article
- Non-English Language Preference as a Social Determinant of Health in Cardiovascular Disease: Addressing the Unseen.JACC. Advances · 2024Article
- Operationalizing Equity, Inclusion, and Access in Research Practice at a Large Academic Institution.Journal of general internal medicine · 2024Article
- Ethical considerations in rapid and novel treatments in psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Automating Clinical Trial Matches Via Natural Language Processing of Synthetic Electronic Health Records and Clinical Trial Eligibility Criteria.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024Article
- Strategies to promote language inclusion at 17 CTSA hubs.Journal of clinical and translational science · 2024Article
- Healthcare experiences of patients with Down syndrome from primarily Spanish-speaking households.American journal of medical genetics. Part A · 2023Article
- Inclusion of Non-English-Speaking Participants in Pediatric Health Research: A Review.JAMA pediatrics · 2023Review
- Inclusion of Non-English-Speaking Participants in Studies of Parkinson's Disease: A Call to Action.Movement disorders : official journal of the Movement Disorder Society · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Underrepresentation of individuals with limited English proficiency (LEP) who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity. This article suggests strategies for increasing representation of Spanish speakers in clinical rials by emphasizing the importance of early engagement with Spanish language communities, inclusive participant recruitment, and collaborative trial design and implementation. Although investigators and institutions administering government-funded research must meet federal requirements for language assistance, journal editors, peer reviewers, institutional review board members, academic health centers, and all beneficiaries of the biomedical and behavioral research enterprise in the United States must motivate linguistic inclusion.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.