Evidence map›Paper›PMID 35405034›Full record

ArticleAmerican journal of hematology2022

Magnetic resonance imaging metrics of oxygen extraction fraction: Contradictions or insight into pathophysiological mechanisms?

Jeffrey N Stout, Pei-Yi Lin, Jason Sutin, John Higgins, P Ellen Grant

Erratum issuedAbstract read
In one paragraph

Article in American journal of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jeffrey N StoutFetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-7342-3018
Pei-Yi LinFetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-3685-3331
Jason SutinFetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
John HigginsCenter for Systems Biology and Department of Pathology, Massachusetts General Hospital Boston, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-9182-0076
P Ellen GrantFetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-1005-4013

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Single-cell measurement of cyclic stress on sickle blood cells by imaging-microfluidicsR01HL158102 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DAO, MING, HIGGINS, JOHN MATTHEW · 2021 to 2024
$2.4M
Gene therapy targeting BCL11A to induce fetal hemoglobin and reduce sickle hemoglobin in patients with Sickle Cell DiseaseOT2HL154815 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI WILLIAMS, DAVID A · 2020 to 2020
$1.2M
Boston Consortium to Cure SCD - Williams/John HigginsOT2HL152639 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI HIGGINS, JOHN MATTHEW, WILLIAMS, DAVID A · 2019 to 2019
$84k
NHLBI NIH HHS OT2 HL152639NHLBI NIH HHS OT2 HL154815NHLBI NIH HHS R01 HL158102NICHD NIH HHS P50 HD105351
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Magnetic Resonance ImagingBrainCerebrovascular CirculationHumansOxygenOxygen ConsumptionOxygen

Identifiers

PMID35405034
PMCPMC10353571

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.