SynthesisJournal of medical Internet research2022
Computerized Cognitive Behavioral Therapy for Treatment of Depression and Anxiety in Adolescents: Systematic Review and Meta-analysis.
Synthesis in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07374653 (Online Cognitive Behavioural Therapy for Adolescents With Depression - A Randomized Controlled Trial), which is not on this map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Online Cognitive Behavioural Therapy for Adolescents With Depression - A Randomized Controlled Trial
Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The intervention effect of internet-based cognitive behavioral therapy on anxiety, depression, and stress in college students: a systematic review and meta-analysis based on randomized controlled trials.Frontiers in psychology · 2026Pooled it
- Updates on digital mental health interventions for children and young people: systematic overview of reviews.European child & adolescent psychiatry · 2025Pooled it
- Effectiveness of technology-assisted vs face-to-face cognitive behavioural therapy for anxiety and depression in children and young people: A systematic review and meta-analysis.Clinical child psychology and psychiatry · 2024Pooled it
- Digital Psychotherapies for Adults Experiencing Depressive Symptoms: Systematic Review and Meta-Analysis.JMIR mental health · 2024Pooled it
- Interventions for anxiety and depression in patients with atopic dermatitis: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Therapist-guided and self-guided internet-based behavioural activation versus treatment as usual for adolescents with depression: randomised controlled trial with economic evaluation.BMJ mental health · 2026Trial
- Digital Cognitive Behavioral Therapy for Chinese Adolescents with Depressive Symptoms (CADS-D): protocol for a randomized controlled trial.BMC psychiatry · 2026Article
- Inclusive Digital Health Strategies for Persons With Disabilities: A Scoping Review.JAMA network open · 2026Article
- The effectiveness of CBT-based NLP-enabled AI conversational agents for mental health intervention: a systematic review and meta-analysis.NPJ digital medicine · 2026Article
- Implementation of digital mental health interventions for children and adolescents: A systematic review.Internet interventions · 2026Review
- Article
- Developing an Internet-Based Cognitive Behavioral Therapy Intervention for Adolescents With Anxiety Disorders: Design, Usability, and Initial Evaluation of the CoolMinds Intervention.JMIR formative research · 2025Article
- Evaluation of a Trial of Computerised Cognitive Behavioural Therapy Programme Within Local Child and Adolescent Mental Health Services.Journal of evaluation in clinical practice · 2025Article
- Efficacy of vigorous physical activity as an intervention for mitigating depressive symptoms in adolescents and young adults: a comprehensive systematic review and meta-analysis.Frontiers in behavioral neuroscience · 2025Review
- A pilot randomized trial comparing face-to-face and internet-based unified transdiagnostic treatment for adolescents with anxiety and depressive disorders in Iran.Frontiers in psychiatry · 2025Article
- Incorporating Complexity and System Dynamics into Economic Modelling for Mental Health Policy and Planning.PharmacoEconomics · 2024Article
- Article
- Diagnosing and tracking depression based on eye movement in response to virtual reality.Frontiers in psychiatry · 2024Article
- Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis.Internet interventions · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDepression and anxiety are major public health concerns among adolescents. Computerized cognitive behavioral therapy (cCBT) has emerged as a potential intervention, but its efficacy in adolescents remains unestablished.
objectiveThis review aimed to systematically review and meta-analyze findings on the efficacy of cCBT for the treatment of adolescent depression and anxiety.
methodsEmbase, PsycINFO, and Ovid MEDLINE were systematically searched for randomized controlled trials in English, which investigated the efficacy of cCBT for reducing self-reported depression or anxiety in adolescents aged 11 to 19 years. Titles, abstracts, and full texts were screened for eligibility by 2 independent researchers (TB and LC). A random-effects meta-analysis was conducted to pool the effects of cCBT on depression and anxiety symptom scores compared with the control groups. Study quality was assessed using the Cochrane Collaboration Risk of Bias tool.
resultsA total of 16 randomized controlled trials were eligible for inclusion in this review, of which 13 (81%) were included in the meta-analysis. The quality of the studies was mixed, with 5 (31%) studies rated as good overall, 2 (13%) rated as fair, and 9 (56%) rated as poor. Small but statistically significant effects of cCBT were detected, with cCBT conditions showing lower symptom scores at follow-up compared with control conditions for both anxiety (standardized mean difference -0.21, 95% CI -0.33 to -0.09; I
conclusionsThis meta-analysis reinforces the efficacy of cCBT for the treatment of anxiety and depression and is the first to examine this exclusively in adolescents. Future research could aim to identify the active components of these interventions toward optimizing their development and increasing the feasibility and acceptability of cCBT in this age group.
trial registrationPROSPERO CRD42019141941; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=141941.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.